Tin tức & Cập nhật

Treatment with oral microbiome SER-109 in patients with recurrent Clostridioides difficile infection (CDI) is well tolerated and appears to reduce recurrence, as shown in a phase III ECOSPOR IV study.

Use of antithrombotic agents (ATs) provides a protective benefit against death in patients with acute upper gastrointestinal bleeding (AUGIB), suggests a study, noting that low-dose aspirin is responsible for such protective effect.

A dietary pattern consisting of preserved vegetables, pickled vegetables, and salted meat appears to increase the risk of mortality among patients with esophageal squamous cell carcinoma (ESCC), reveals a recent study. In contrast, fish and shrimp intake may offer a protective benefit.

The novel potassium-competitive acid blocker zastaprazan (JP-1366) appears to have a rapid and potent gastric acid-suppressive effect, with a single oral dose up to 60 mg and multiple oral doses up to 40 mg being safe and well tolerated, according to a study.

Clinicians should consider de-escalating combination therapy with immunomodulators to a monotherapy after 1 year in patients with inflammatory bowel disease (IBD), says an expert at Crohn’s and Colitis Congress 2023.

The use of liposomal irinotecan in combination with 5-fluorouracil, leucovorin, and oxaliplatin (NALIRIFOX regimen) significantly improved overall survival (OS) and progression-free survival (PFS) in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) compared with gemcitabine plus nab-paclitaxel (Gem+NabP) in the first-line setting, according to the NAPOLI-3* trial presented at the ASCO GI 2023.