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High-dose iron infusion corrects deficiency, maintains iron stores in pregnancy
A single 1,000-mg infusion of ferric carboxymaltose (FCM) effectively resolves iron deficiency in pregnancy, preserving iron stores and reducing the need for repeat infusions as compared with the lower FCM dose, as shown in a study.
Trabectedin fails to improve survival outcomes in recurrent ovarian, primary peritoneal, or fallopian tube cancer
Trabectedin did not improve overall survival (OS) or progression-free survival (PFS) compared with chemotherapy in women with recurrent ovarian, primary peritoneal, or fallopian tube cancer and BRCA mutation or BRCAness phenotypes, according to results of the phase III MITO23 trial.
Levonorgestrel-releasing intrauterine system reduces pelvic pain but may increase expulsion risk
In the treatment of patients with organic disease and heavy menstrual bleeding and/or dysmenorrhea, the use of levonorgestrel-releasing intrauterine system (LNG-IUS) attenuates chronic pelvic pain, according to a study. However, it appears to confer an increased risk of expulsion for some women.