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In patients hospitalized for COVID-19, use of statins prior to admission is predictive of improved outcomes and lower inflammation, according to a study.

Statins help improve outcomes in hospitalized COVID-19 patients

16 Dec 2024

Add-on mifepristone for early pregnancy loss lowers chances of treatment failure

In the treatment of women with early pregnancy loss, adding mifepristone to misoprostol helps reduce the incidence of treatment failure as compared with misoprostol alone, according to a retrospective study.

Add-on mifepristone for early pregnancy loss lowers chances of treatment failure

Psilocybin: A new paradigm for treating postpandemic depression?

16 Dec 2024 bởi

Healthcare workers who developed depression in the course of frontline work during the COVID-19 pandemic experienced substantial reductions in symptoms following psilocybin treatment, as shown in a small randomized clinical trial.

Psilocybin: A new paradigm for treating postpandemic depression?

Fostamatinib of no benefit in COVID-19 patients with hypoxemia

In the treatment of hospitalized adults with COVID-19 and hypoxemia, the use of the spleen tyrosine kinase inhibitor fostamatinib does not appear to have any positive effect on the number of oxygen-free days as compared with placebo, according to the results of a phase III trial.

Fostamatinib of no benefit in COVID-19 patients with hypoxemia

No increased risk of brain bleed with DOAC vs antiplatelet therapy in AF patients

In the treatment of patients with atrial fibrillation (AF), direct oral anticoagulants (DOACs) do not contribute to an increased risk of intracranial haemorrhage compared with antiplatelet therapy, according to the results of a systematic review and meta-analysis.

No increased risk of brain bleed with DOAC vs antiplatelet therapy in AF patients

Salbutamol may lower risk, improve prognosis of prostate cancer

The incidence of prostate cancer is reduced among individuals treated with salbutamol, a short-acting beta-2 adrenergic agonist, according to a study.

Salbutamol may lower risk, improve prognosis of prostate cancer

14 Dec 2024

$Novel EZH1/2 dual inhibitor shows activity against relapsed/refractory T-cell lymphoma$

Novel EZH1/2 dual inhibitor shows activity against relapsed/refractory T-cell lymphoma

Dual inhibition of EZH1/2 with valemetostat appears to induce responses in patients with relapsed or refractory peripheral T-cell lymphoma while having a manageable safety profile, according to the results of a single-arm phase II trial.

Novel EZH1/2 dual inhibitor shows activity against relapsed/refractory T-cell lymphoma

Elafibranor improves transplant-free survival in patients with PBC

14 Dec 2024 bởi

Among patients with primary biliary cholangitis (PBC), treatment with elafibranor improved predicted transplant-free survival rates based on improvements in GLOBE and UK-PBC scores, according to the phase III ELATIVE trial presented at The Liver Meeting 2024.

Elafibranor improves transplant-free survival in patients with PBC