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A pilot study of stewardship has found that the use of psychoactive medications (PMs) is commonly continued during transitions of care, often without knowledge of the initial indication.

Psychoactive medication use frequently continued beyond discharge

Adjuvant dabrafenib-trametinib confers durable RFS benefit for resected stage III melanoma

03 Dec 2020 bởi

Adjuvant therapy with the BRAF inhibitor dabrafenib and the MEK inhibitor trametinib for 12 months led to long-term relapse-free survival (RFS) with no apparent long-term toxicities in patients with resected stage III melanoma with BRAF V600E or V600K mutations, according to the extended follow-up results of the phase III COMBI-AD* trial.

Adjuvant dabrafenib-trametinib confers durable RFS benefit for resected stage III melanoma

Heat or miss: Peripheral thermometers underestimate body temperature

03 Dec 2020 bởi

Peripheral thermometers, such as those used on the ear and armpits, are specific but not sensitive, and may be insufficient to rule out a fever, according to a recent meta-analysis.

Heat or miss: Peripheral thermometers underestimate body temperature

Parents of NICU babies highly depressive

Parents of infants admitted into the neonatal intensive care unit (NICU) show high levels of depressive symptoms at discharge even if their baby was born at term, a recent study has found.

Parents of NICU babies highly depressive

Are people with HIV at greater risk of COVID-19 mortality?

People with HIV (PWH) who are hospitalized due to COVID-19 may have an increased mortality risk, according to a study from the UK.

Are people with HIV at greater risk of COVID-19 mortality?

COVID-19 patients exhale millions of virus in early stages

COVID-19 patients carry particularly high viral loads during the early stages of the disease, with millions of virus exhaled in their breath per hour, reveals a study — which indicates that breath emission could possibly contribute to airborne transmission of the virus.

COVID-19 patients exhale millions of virus in early stages

Concurrent vasopressor, nephrotoxic agents up risk of AKI in critically ill youths on vancomycin

Nearly half of critically ill adolescent and young adult patients who received vancomycin develop acute kidney injury (AKI), according to a study.

Concurrent vasopressor, nephrotoxic agents up risk of AKI in critically ill youths on vancomycin

4-week treatment delay ups mortality in cancer patients

A 4-week delay in cancer treatment can increase mortality across surgical, systemic treatment, and radiotherapy indications for seven cancers, with longer delays being more and more harmful to patients, suggest the results of a systematic review and meta-analysis.

4-week treatment delay ups mortality in cancer patients

Crushed prasugrel offers no reperfusion benefit prior to PCI

Giving crushed prasugrel to patients with ST-segment elevation myocardial infarction (STEMI) en route to the hospital for planned PCI* does not improve reperfusion rates compared with giving the tablets whole in the COMPARE CRUSH trial.

Crushed prasugrel offers no reperfusion benefit prior to PCI

SELECT model predicts survival in Asian patients with malignant pleural effusion

A study has found that the LENT, modified-LENT, and PROMISE scores have poor accuracy of survival prognostication in Asian patients with malignant pleural effusion (MPE) undergoing pleuroscopy.

SELECT model predicts survival in Asian patients with malignant pleural effusion