Tin tức & Cập nhật

Bispecific antibody overcomes P. aeruginosa infection in patients with bronchiectasis

The bispecific antibody gremubamab, which targets two proteins on the surface of Pseudomonas aeruginosa, has been shown to substantially reduce bacterial load and improve quality of life for infected bronchiectasis patients in the phase II GREAT-2 study.

Dual-target vaccine for flu, COVID-19 compares favourably with standalone comparators

The investigational influenza–COVID-19 combination vaccine mRNA-1083 has demonstrated noninferiority to recommended standard-care flu and COVID-19 vaccines, with higher immune responses and an acceptable safety profile in adults at least 50 years of age, according to the results of a phase III trial.

Digital therapy improves life quality of patients with pulmonary fibrosis

A novel digital psychological therapy, named Almee, demonstrates efficacy in improving health-related quality of life (HRQOL) in patients with pulmonary fibrosis, irrespective of antifibrotic treatment use, reports a study presented at ATS 2025.

RSV-ARI nearly triples mortality risk in new study

Acute respiratory infection caused by respiratory syncytial virus (RSV-ARI) nearly triples the risk of death, particularly among individuals with chronic underlying respiratory conditions, as shown in a nationwide cohort study in Denmark.

Low-dose morphine may do more harm than good for COPD patients with chronic breathlessness

Treatment with steady-state, low-dose morphine does not appear to improve sleep efficiency, sleep-disordered breathing frequency, or next-day alertness but may rather result in hypoventilation during sleep in chronic obstructive pulmonary disease (COPD) patients with chronic breathlessness, according to the results of a randomized, double-anonymized, crossover trial.

Protecting the vulnerable: The role of oral antivirals in COVID-19 management

At the Asia Vaccines and Antivirals Summit (AVAS) 2025 held in Bangkok, Thailand, two expert-led sessions provided valuable perspectives on the expanding role of oral antivirals in COVID-19 management. Dr Daniel Griffin, an infectious disease specialist and Clinical Instructor of Medicine at Columbia University, New York, US, focused on protecting high-risk populations through the timely use of antiviral therapy. Complementing this, Professor Ching-Tai Huang of Chang Gung University and Memorial Hospital in Taiwan offered practical guidance on clinical management strategies, including patient risk stratification and therapeutic selection.

Cough variant asthma: A diagnostic challenge with a simple solution

Multiple antibiotic exposures in early life may have long-term respiratory consequences

Preterm infants with multiple episodes of antibiotic exposure prenatally have a higher likelihood of having impaired lung function at early school age, as shown in a study.