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Managing rheumatoid arthritis in primary care

Managing rheumatoid arthritis in primary care

24 Feb 2020 bởi

Early diagnosis of RA is important such that treatment can be initiated early to prevent joint damage. Senior consultant Dr Faith Chia Li-Ann and senior resident Dr Paula P Tjokrosaputro from the Department of Rheumatology, Allergy and Immunology in Tan Tock Seng Hospital (TTSH), Singapore share their insights with Pearl Toh on the role of GPs in caring for patients with RA in the primary care setting.

Managing rheumatoid arthritis in primary care

Arteriovenous fistula or graft dysfunction more likely in ADPKD patients in the long run

Arteriovenous fistula or graft dysfunction more likely in ADPKD patients in the long run

Patients with autosomal dominant polycystic kidney disease (ADPKD) are at a lower risk of arteriovenous fistula or graft (AVF/AVG) dysfunction in the short term, but suffer from an excess risk in the long-term, a recent study has found.

Arteriovenous fistula or graft dysfunction more likely in ADPKD patients in the long run

Undernutrition a culprit for reduced physical function, disability in older adults

Undernutrition a culprit for reduced physical function, disability in older adults

Older adults who are undernourished are likely to have poorer physical function and disability compared with their peers who have normal nutrition, a study has found.

Undernutrition a culprit for reduced physical function, disability in older adults

Pathological fear of cancer recurrence higher among Singapore vs Western survivors

Pathological fear of cancer recurrence higher among Singapore vs Western survivors

24 Feb 2020 bởi

Among cancer survivors, fear of cancer recurrence (FCR) in Singapore is comparable to that of Western counterparts, but severe or pathological levels of FCR are fourfold higher, reveals a study, underscoring a difficulty not commonly acknowledged but deserves more attention.

Pathological fear of cancer recurrence higher among Singapore vs Western survivors

Increase dosage of antihypertensive agents to improve CV outcomes, says study

Increase dosage of antihypertensive agents to improve CV outcomes, says study

A recent study has shown no improvement in the rate of blood pressure (BP) control despite an increase in the prevalence of antihypertensive medication use.

Increase dosage of antihypertensive agents to improve CV outcomes, says study

TENS shows promise for women with fibromyalgia

TENS shows promise for women with fibromyalgia

24 Feb 2020 bởi

Use of transcutaneous electrical nerve stimulation (TENS) led to a significant improvement in movement-evoked pain and fatigue in women with fibromyalgia, according to the FAST* study.

TENS shows promise for women with fibromyalgia

Osimertinib preferable in first-line treatment of EGFR-mutant NSCLC

Osimertinib preferable in first-line treatment of EGFR-mutant NSCLC

24 Feb 2020 bởi

Nonsmall cell lung cancer (NSCLC) patients harbouring sensitive EGFR mutations may fare well with the third-generation tyrosine kinase inhibitor osimertinib as an upfront therapy, with the results of a network meta-analysis showing that the drug tops other currently available options in terms of progression-free survival and tolerability.

Osimertinib preferable in first-line treatment of EGFR-mutant NSCLC

HCV clearance may improve glucose metabolism

HCV clearance may improve glucose metabolism

Abnormal glycometabolism is more common among patients with hepatitis C virus (HCV) infection, and viral clearance may improve glucose control, a recent study has found.

HCV clearance may improve glucose metabolism

$CXCR4–CXCL12 axis blockade with ulocuplumab safe in relapsed/refractory myeloma$

CXCR4–CXCL12 axis blockade with ulocuplumab safe in relapsed/refractory myeloma

The first-in-class fully human IgG4 monoclonal antibody ulocuplumab that inhibits the binding of CXCR4 to CXCL12 appears to be safe in the treatment of patients with relapsed/refractory myeloma, yielding a high response rate when added to lenalidomide and dexamethasone with acceptable adverse events, according to the results of a phase Ib/II trial.

CXCR4–CXCL12 axis blockade with ulocuplumab safe in relapsed/refractory myeloma

Propranolol does not shorten duration of labour induction in nulliparous women

Propranolol does not shorten duration of labour induction in nulliparous women

24 Feb 2020 bởi

Administering intravenous propranolol hydrochloride does not reduce the duration of labour induction for nulliparous women who undergo vaginal delivery, according to a study presented at SMFM 2020.

Propranolol does not shorten duration of labour induction in nulliparous women

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