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Chlormadinone prolongs active surveillance, maintains QoL in men with prostate cancer
Use of the oral antiandrogen chlormadinone at a low dose led to improvements in persistence rate of active surveillance (AS), PSA* and testosterone levels and prostate volume, and quality of life (QoL) in men with low-risk prostate cancer (PCa), the PROSAS study has shown.
Chlormadinone prolongs active surveillance, maintains QoL in men with prostate cancer
05 Nov 2021Nerve block may provide relief for pancreatic cancer pain
Neurolytic splanchnic nerve block (SNB) appears effective for pain control in patients with moderate-to-severe pain due to unresectable pancreatic cancer, a study has shown.
Nerve block may provide relief for pancreatic cancer pain
04 Nov 2021RS-RARP confers better continence outcomes than conventional RARP
In prostate cancer patients, retzius-sparing robotic-assisted radical prostatectomy (RS-RARP) yields better continence outcomes compared with conventional RARP, a recent study has found.
RS-RARP confers better continence outcomes than conventional RARP
03 Nov 2021Weight loss boosts response to intrauterine progestin
Among women with obesity and atypical hyperplasia or low-risk endometrial cancer, weight loss during conservative management with intrauterine progestin improves treatment outcomes, according to a study.
Weight loss boosts response to intrauterine progestin
03 Nov 2021SCLC: Hippocampal avoidance in prophylactic cranial irradiation a potential SoC
In patients with small-cell lung cancer (SCLC), hippocampal avoidance-prophylactic cranial irradiation (HA-PCI) better preserves cognitive function and has no adverse impact on the incidence of brain metastases, overall survival (OS) and quality of life (QoL) compared with standard PCI, a phase III randomized controlled trial has shown.
SCLC: Hippocampal avoidance in prophylactic cranial irradiation a potential SoC
03 Nov 2021Omission of parametrial boost does not compromise local control, survival in modern era
Leaving out the use of external beam parametrial boost (EBPB) for locally advanced cervical cancer does not seem to negatively affect local control or survival in the era of image-guided brachytherapy, results of a study have shown. This then supports a reduced need for standardized use of parametrial boost.
Omission of parametrial boost does not compromise local control, survival in modern era
02 Nov 2021Hepatic arterial infusion chemo improves OS vs TACE in large HCC
Hepatic arterial infusion chemotherapy (HAIC) with fluorouracil, leucovorin and oxaliplatin (FOLFOX) as first-line treatment significantly improves overall survival (OS) vs transarterial chemoembolization (TACE) in patients with large, unresectable hepatocellular carcinoma (HCC), a phase III trial in China has shown.
Hepatic arterial infusion chemo improves OS vs TACE in large HCC
02 Nov 2021Pembrolizumab extends RFS in stage II melanoma
Pembrolizumab extended recurrence-free survival (RFS) in patients with high-risk stage II melanoma who had undergone complete resection, interim analysis results of the phase III KEYNOTE-716 trial showed.