Tin tức & Cập nhật

Survival benefit in patients with de novo stage IV nonsmall-cell lung cancer (NSCLC) depends on the type of treatment received, with significantly better median overall survival (OS) seen with the use of small-molecule targeted therapy against epidermal growth factor receptor mutations and anaplastic lymphoma kinase rearrangements than with best supportive care, reports a study.

The width of the spared neurovascular bundle (NVB) is an important indicator of postoperative sexual function after robot-assisted laparoscopic prostatectomy for prostate cancer, a recent study has found. These findings point to NVB as an easy intraoperative marker for assessing postoperative outcomes.

Triplet therapy combining androgen deprivation therapy (ADT), docetaxel, and abiraterone-prednisone improves overall survival (OS) in men with de novo metastatic castration-sensitive prostate cancer (mCSPC), according to results of the phase III PEACE-1 trial presented at ESMO 2021.

Acid suppression (AS) medications, such as proton pump inhibitors (PPIs) and histamine type-2 receptor antagonists (H2RAs), weaken the efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) in nonsmall cell lung cancer (NSCLC), resulting in worse survival outcomes, according to a recent Singapore meta-analysis.