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Preoperative treatment with the oral nonsteroidal selective ER degrader elacestrant appears to yield biological and molecular responses in early-stage breast cancer, while having a manageable safety profile, as shown in a phase I trial.

Elacestrant shows promising antitumour activity in early breast cancer

Early-life ozone exposure linked to asthma, wheeze in children

Exposure to relatively low ambient ozone at ground level (O3) during early life appears to carry an increased risk of asthma and wheeze outcomes at age 4–6 years, as reported in a study.

Early-life ozone exposure linked to asthma, wheeze in children

Antidepressant combos deliver improved outcomes in TRD

06 Apr 2025 bởi

Combination treatment with esketamine plus either a selective serotonin reuptake inhibitor (SSRI) or a serotonin-norepinephrine reuptake inhibitor (SNRI) is beneficial in treatment-resistant depression (TRD), with notable variations in outcomes depending on the choice of antidepressant class, as shown in a large retrospective study.

Antidepressant combos deliver improved outcomes in TRD

06 Apr 2025

Low sexual activity may raise depression risk in women

06 Apr 2025

Women who rarely engage in sexual activity appear to be at greater odds of developing depression, according to a US study, noting a potentially bidirectional association.

Low sexual activity may raise depression risk in women

06 Apr 2025

Two-ingredient diaper wipes gentle on skin affected by eczema

05 Apr 2025 bởi

Wipes formulated with purified water plus fruit extract for sensitive skin are safe to use on babies with eczema-prone skin or active eczema, according to a study.

Two-ingredient diaper wipes gentle on skin affected by eczema

TTSS system closes gastrointestinal defects after endoscopy

The recently approved through-the-scope suturing (TTSS) system demonstrates safety and efficacy in the closure of mucosal defects following therapeutic endoscopic interventions, reports a recent study.

TTSS system closes gastrointestinal defects after endoscopy

Over-the-counter magnesium supplements help lower cardiovascular risk in diabetes

Long-term use of over-the-counter magnesium supplements appears to have cardioprotective benefits in patients with diabetes, having been shown to reduce the risk of heart failure (HF) and major adverse cardiac events, according to a study.

Over-the-counter magnesium supplements help lower cardiovascular risk in diabetes

Activity type matters for children’s cognitive development

04 Apr 2025 bởi

Physical activity, outdoor play, and reading books boost children's cognitive development, but excess physical activity may harm academic performance if it cuts into sleep time, as shown in a study from Singapore.

Activity type matters for children’s cognitive development

Mediterranean diet helps prevent anxiety, depression in people with obesity

Adherence to the Mediterranean diet results in a reduction in the risks of anxiety and depression among individuals with obesity, a recent study has shown.

Mediterranean diet helps prevent anxiety, depression in people with obesity

Dietary diversity helps lower bad cholesterol in women

04 Apr 2025 bởi

Adherence to a diet containing a variety of foods may improve serum lipid markers, suggests a study involving Japanese female workers.

Dietary diversity helps lower bad cholesterol in women