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A clinically significant association exists between metabolic syndrome (MetS) and pulse wave velocity (PWV), as well as an increasing trend in PWV values for each increase in MetS-related cardiometabolic risk factors (CMRFs), according to a study.

Metabolic syndrome ups risk of arterial stiffness

Later menopause linked to lower stroke risk

Women with increasing age at menopause are at decreased risk of total and ischaemic stroke, a study has found.

Later menopause linked to lower stroke risk

Clopidogrel bests aspirin as maintenance monotherapy post-PCI

10 Jun 2021 bởi

Long-term maintenance monotherapy with clopidogrel is superior to aspirin in reducing the risk of both ischaemic and major bleeding events in patients who had successfully undergone 6–18 months of DAPT* without any clinical event following a percutaneous coronary intervention (PCI), the head-to-head HOST-EXAM** trial has shown.

Clopidogrel bests aspirin as maintenance monotherapy post-PCI

Methotrexate use lowers CVD risk in RA patients on biologics

Concomitant use of methotrexate (MTX) among patients with rheumatic arthritis (RA) initiating biologics results in a 24-percent reduced risk of cardiovascular disease (CVD) events, a study has shown.

Methotrexate use lowers CVD risk in RA patients on biologics

Heat-not-burn cigarettes lighter on the heart

Heat-not-burn cigarettes (HNBCs) seem to have a less detrimental effect on cardiovascular function compared to traditional tobacco cigarettes (Tcig), a recent study has found.

Heat-not-burn cigarettes lighter on the heart

Study does not support urate lowering for managing hypertension in young people

Urate-lowering therapy with allopurinol does little to reduce blood pressure or inflammation levels in young adults despite improvements in flow-mediated dilation, according to a study.

Study does not support urate lowering for managing hypertension in young people

Pirfenidone PIROUETTES from treating lung to heart scarring

10 Jun 2021 bởi

The oral antifibrotic agent pirfenidone – a drug currently approved for the treatment of idiopathic lung fibrosis – significantly reduced scarring of the heart muscle in individuals with chronic heart failure with preserved ejection fraction (HFpEF) and myocardial fibrosis, according to findings from the early-phase PIROUETTE trial presented at ACC.21.

Pirfenidone PIROUETTES from treating lung to heart scarring

Sirolimus improves survival in paediatric pulmonary vein stenosis

Use of systemic sirolimus therapy (SST) provides a survival benefit in infants and children with moderate-to-severe pulmonary vein stenosis (PVS) that persists even after adjusting the analysis for survival bias, a study has found.

Sirolimus improves survival in paediatric pulmonary vein stenosis

BP increases with age, but medication helps

09 Jun 2021 bởi

A positive association exists between blood pressure (BP) and age, with nearly threefold variation across subgroups, indicating differences in biology, behaviour, or exposures, reports a study. However, use of antihypertensive medication strongly attenuates this association and weakens the variation.

BP increases with age, but medication helps

Moderate aortic stenosis ups death risk in HFrEF patients

Moderate aortic stenosis (AS) has been linked to a significantly higher risk of mortality in patients with heart failure (HF) with reduced left ventricular ejection fraction (LVEF; HFrEF), reveals a study. Aortic valve replacement (AVR), especially transcatheter AVR during follow-up, appears to improve survival in patients with HFrEF and moderate AS.

Moderate aortic stenosis ups death risk in HFrEF patients