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RA onset delayed through 4 years with 1-year abatacept treatment in at-risk individuals

16 Jul 2025 bởi

A 12-month therapeutic intervention with self-administered abatacept can delay the onset of rheumatoid arthritis (RA) in at-risk individuals for up to 4 years, according to results from the ALTO follow-up study presented at EULAR 2025.

RA onset delayed through 4 years with 1-year abatacept treatment in at-risk individuals

16 Jul 2025

Nurulimab-prolgolimab superior to prolgolimab alone in metastatic melanoma

11 Jul 2025 bởi

First-line nurulimab and prolgolimab combination therapy demonstrated superior efficacy compared with prolgolimab monotherapy in patients with unresectable or metastatic melanoma, according to the OCTAVA trial presented at AACR 2025.

Nurulimab-prolgolimab superior to prolgolimab alone in metastatic melanoma

11 Jul 2025

Pembrolizumab + CCRT ups survival in high-risk LACC

10 Jul 2025 bởi

Treatment with the combination of pembrolizumab and concurrent chemoradiotherapy (CCRT), followed by pembrolizumab maintenance, led to a sustained, long-term survival benefit in patients with high-risk, locally advanced cervical cancer (LACC) compared with CCRT alone, according to the final analysis of the phase III ENGOT-cx11/GOG-3047/KEYNOTE-A18 trial presented at ASCO 2025.

Pembrolizumab + CCRT ups survival in high-risk LACC

10 Jul 2025

Does testosterone level predict metastasis-free survival in nmCRPC?

09 Jul 2025

Maintenance serum testosterone levels ≥20 ng/dL do not appear predictive of worse metastasis-free survival (MFS) among men with testosterone <50 ng/dL on first-line therapy of nonmetastatic castration-resistant prostate cancer (nmCRPC) using novel hormonal agents, according to a study.

Does testosterone level predict metastasis-free survival in nmCRPC?

09 Jul 2025

Structured exercise after adjuvant chemotherapy for colon cancer extend overall survival

09 Jul 2025 bởi

A structured exercise programme offered alongside health education materials may prolong overall survival (OS) in patients with resected colon cancer who have completed adjuvant chemotherapy, according to the final results of the phase III CHALLENGE trial presented at ASCO 2025.

Structured exercise after adjuvant chemotherapy for colon cancer extend overall survival

09 Jul 2025

Linperlisib plus chidamide shows therapeutic potential in cutaneous T-cell lymphoma

08 Jul 2025

Combination treatment with the PI3Kδ inhibitor linperlisib plus the histone deacetylase inhibitor chidamide has demonstrated promising clinical activity in relapsed or refractory cutaneous T-cell lymphoma (CTCL) in a phase I study.

Linperlisib plus chidamide shows therapeutic potential in cutaneous T-cell lymphoma

08 Jul 2025

Aspirin use may prevent CRC metastasis

07 Jul 2025

The use of aspirin appears to provide protective benefits against metastasis in patients with colorectal cancer (CRC), reports a study.

Aspirin use may prevent CRC metastasis

07 Jul 2025

Topical BRAF inhibitor relieves EGFR-induced acneiform eruption

07 Jul 2025 bởi

LUT014 gel, a novel, small-molecule, topical formulation of a BRAF inhibitor, relieves acneiform rash toxicities from anti-EGFR therapies, findings from a phase II study suggest.

Topical BRAF inhibitor relieves EGFR-induced acneiform eruption

07 Jul 2025

Hormone therapy's impact on young-onset breast cancer risk varies by type

06 Jul 2025

New research shows that using oestrogen hormone therapy alone may reduce the risk of young-onset breast cancer, while combining it with progestin could result in a risk increase among women with intact uterus and ovaries.

Hormone therapy's impact on young-onset breast cancer risk varies by type

06 Jul 2025

CDK4/6 inhibitor-induced liver injury common in breast cancer

05 Jul 2025 bởi

Liver injury occurs in around one in 20 patients treated with cyclin-dependent kinase 4/6 inhibitors for metastatic breast cancer, according to a multicentre retrospective study in Spain.

CDK4/6 inhibitor-induced liver injury common in breast cancer

05 Jul 2025

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RA onset delayed through 4 years with 1-year abatacept treatment in at-risk individuals

RA onset delayed through 4 years with 1-year abatacept treatment in at-risk individuals

Nurulimab-prolgolimab superior to prolgolimab alone in metastatic melanoma

Nurulimab-prolgolimab superior to prolgolimab alone in metastatic melanoma

Pembrolizumab + CCRT ups survival in high-risk LACC

Pembrolizumab + CCRT ups survival in high-risk LACC

Does testosterone level predict metastasis-free survival in nmCRPC?

Does testosterone level predict metastasis-free survival in nmCRPC?

Structured exercise after adjuvant chemotherapy for colon cancer extend overall survival

Structured exercise after adjuvant chemotherapy for colon cancer extend overall survival

Linperlisib plus chidamide shows therapeutic potential in cutaneous T-cell lymphoma

Linperlisib plus chidamide shows therapeutic potential in cutaneous T-cell lymphoma

Aspirin use may prevent CRC metastasis

Aspirin use may prevent CRC metastasis

Topical BRAF inhibitor relieves EGFR-induced acneiform eruption

Topical BRAF inhibitor relieves EGFR-induced acneiform eruption

Hormone therapy's impact on young-onset breast cancer risk varies by type

Hormone therapy's impact on young-onset breast cancer risk varies by type

CDK4/6 inhibitor-induced liver injury common in breast cancer

CDK4/6 inhibitor-induced liver injury common in breast cancer