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The anti-interleukin (IL)-36 receptor monoclonal antibody spesolimab not only helps treat generalized pustular psoriasis (GPP) flares but also prevent them, according to the results of the Effisayil 2 study presented at WCD 2023.

Spesolimab curbs flares in generalized pustular psoriasis

$Tocilizumab an effective substitute to anti-TNF agents in refractory Behçet disease$

Tocilizumab an effective substitute to anti-TNF agents in refractory Behçet disease

Tocilizumab (TCZ) may be used as an alternative treatment to antitumour necrosis factor (anti-TNF) agents for patients with Behçet disease (BD)-related uveitis and neurological manifestations, a recent study has shown.

Tocilizumab an effective substitute to anti-TNF agents in refractory Behçet disease

Does polypharmacy affect survival in older patients with haematological malignancy?

Polypharmacy does not appear to result in poorer treatment response and survival in older patients with different haematological malignancies, as shown in a study presented at the recent EHA 2023.

Does polypharmacy affect survival in older patients with haematological malignancy?

Certain drugs, antinuclear antibodies linked to GI dysfunction in SSc

A phenome-wide association study (pheWAS) has found known and potentially new risk factors for gastrointestinal (GI) dysfunction in systemic sclerosis (SSc), which include drug classes such as opioid, antimuscarinic, and endothelin receptor antagonist, and antinuclear antibodies (ANAs) subgroup.

Certain drugs, antinuclear antibodies linked to GI dysfunction in SSc

Novel hepcidin mimetic shows remarkable potential for polycythemia vera

In the three-part, phase II REVIVE study, the investigational, first-in-class hepcidin mimetic rusfertide was highly effective in regulating haematocrit levels in individuals with polycythemia vera (PV) who had a high phlebotomy burden.

Novel hepcidin mimetic shows remarkable potential for polycythemia vera

Vorasidenib may be chemo–RT-sparing in certain low-grade gliomas

The oral drug vorasidenib delays disease progression compared with placebo in patients with residual or recurrent grade 2 gliomas harbouring an isocitrate dehydrogenase 1 or 2 (IDH1 or IDH2) mutation in the phase III INDIGO trial.

Vorasidenib may be chemo–RT-sparing in certain low-grade gliomas

Smoking ups prevalence of hip involvement in ankylosing spondylitis

Cigarette smoking is independently associated with a higher prevalence of hip joint involvement in ankylosing spondylitis (AS), suggests a study.

Smoking ups prevalence of hip involvement in ankylosing spondylitis

Pulsed field ablation for AF works for most patients

Treatment of atrial fibrillation (AF) with catheter ablation using pulsed field energy appears to be beneficial in more than three-fourths of patients, as shown in a study.

Pulsed field ablation for AF works for most patients

Low-glycaemic index foods help improve outcomes in women at high risk of GDM

Women who are at high risk of gestational diabetes mellitus (GDM) appear to benefit from having a low-glycaemic index (GI) or low glycaemic load diet, with a recent study showing that such a diet can control maternal weight gain and reduce the incidence of adverse neonatal outcomes.

Low-glycaemic index foods help improve outcomes in women at high risk of GDM

CBT improves life quality of patients with symptomatic paroxysmal AF

Online cognitive behavioural therapy (CBT) helps improve quality of life (QoL) and reduce healthcare use in patients with symptomatic paroxysmal atrial fibrillation (AF), suggests a study.

CBT improves life quality of patients with symptomatic paroxysmal AF