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Novel genetic marker predicts CHD risk in Chinese patients with T2DM
Researchers from the Chinese University of Hong Kong (CUHK) have discovered PDE1A rs10171703 as a novel genetic marker for coronary heart disease (CHD) in Chinese patients with type 2 diabetes mellitus (T2DM), indicating its potential utility for predicting CHD risk in this patient population.
Novel genetic marker predicts CHD risk in Chinese patients with T2DM
27 Jun 2023Sacituzumab govitecan proven safe, effective in metastatic breast cancer
Treatment with sacituzumab govitecan (SG) demonstrates clinically meaningful overall survival (OS) over single-agent chemotherapy in patients with pretreated, endocrine-resistant, hormone receptor–positive/HER2-negative (HR+/HER2–) metastatic breast cancer (mBC), as confirmed by the final OS analysis from the TROPiCS-02 study, presented at ASCO 2023.
Sacituzumab govitecan proven safe, effective in metastatic breast cancer
26 Jun 2023Debunking the myth: There is no ‘obesity paradox’, new data suggest
Using alternative anthropometric measurements, a post hoc analysis that used data from the PARADIGM-HF* trial debunked the BMI-related ‘obesity paradox’ in a large cohort of patients with chronic heart failure with reduced ejection fraction (HFrEF).
Debunking the myth: There is no ‘obesity paradox’, new data suggest
26 Jun 2023Pembrolizumab well tolerated, effective in NSCLC with autoimmune disease
Use of pembrolizumab is well tolerated in nonsmall cell lung cancer (NSCLC) patients with previous autoimmune diseases, with a nonsignificant trend toward improved outcomes, reports a study.
Pembrolizumab well tolerated, effective in NSCLC with autoimmune disease
25 Jun 2023Neutrophilia, leukocytosis tied to poor outcomes in paediatric liver abscess
In children with liver abscess, factors such as age-related leukocytosis, neutrophilia, elevated aspartate transaminase or alanine transaminase, and hypoalbuminaemia at presentation are significantly associated with poor outcomes, suggests a study.