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Updated CodeBreak 200 analyses boost sotorasib role in KRASG12C-mutant NSCLC
In the PRO analyses of the phase III CodeBreak 200 trial, the first-in-class KRASG12C inhibitor sotorasib improved quality of life (QoL) of patients with pretreated KRASG12C-mutated advanced non-small-cell lung cancer (NSCLC) compared with docetaxel.
Updated CodeBreak 200 analyses boost sotorasib role in KRASG12C-mutant NSCLC
19 Jun 2023Maternal OCD tied to adverse pregnancy, delivery, neonatal outcomes
Pregnant women with obsessive–compulsive disorder (OCD) are at higher risk of adverse pregnancy, delivery, and neonatal outcomes, including gestational diabetes, pre-eclampsia, caesarean delivery, preterm birth, neonatal respiratory distress, neonatal infections, and major congenital malformations, among others, as reported in a study.
Maternal OCD tied to adverse pregnancy, delivery, neonatal outcomes
19 Jun 2023Family-based treatment helps with weight loss in children with overweight, obesity
The implementation of family-based treatment for overweight or obesity in paediatric primary care settings has demonstrated success, with a recent study showing that the treatment led to improved weight outcomes.
Family-based treatment helps with weight loss in children with overweight, obesity
17 Jun 2023Cumulative immunomodulator exposure may heighten risk of CIN2+ in IBD
Among women with inflammatory bowel disease (IBD), those who have long-term immunomodulator exposure are at increased risk of high-grade cervical intraepithelial neoplasia and cervical cancer (CIN2+), according to a study.