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Triple G agonist shows therapeutic potential in obesity
Treatment with retatrutide, the novel agonist of the glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and glucagon receptors, leads to marked reductions in body weight in individuals with obesity, as shown in the results of a phase II trial.
Triple G agonist shows therapeutic potential in obesity
11 Sep 2023Female sex protective against obesity-driven dysregulation of glucose metabolism
Insulin sensitivity and secretion differ by sex among Asians without diabetes, reveals a study, noting that female sex is protective on obesity-driven dysregulation of glucose metabolism.
Female sex protective against obesity-driven dysregulation of glucose metabolism
04 Sep 2023Is intermittent dietary carbohydrate restriction more effective than calorie restriction?
Individuals who adhere to intermittent low-carbohydrate diet (ILCD) show no difference in changes from baseline in obesity measures, glucose regulation, and inflammation compared with those on intermittent calorie restriction diet (ICR) despite trends in reduction in these parameters, a study has shown. However, some differences in responses in lipids and gut microbiota have been observed.