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Pooled data support ruxolitinib cream for treating prurigo nodularis

23 Oct 2025 bởi

Twice-daily application of ruxolitinib cream led to early and sustained improvement in the signs and symptoms of prurigo nodularis in adults, according to the pooled phase III TRuE-PN1 and TRuE-PN2 studies presented at EADV 2025.

Pooled data support ruxolitinib cream for treating prurigo nodularis

23 Oct 2025

Ammoxetine for major depressive disorder clears phase II study

22 Oct 2025

In the treatment of patients with major depressive disorder (MDD), ammoxetine is well tolerated and shows superior efficacy relative to placebo, as shown in a phase II study conducted in China.

Ammoxetine for major depressive disorder clears phase II study

22 Oct 2025

Mangoes serve up metabolic health benefits for adults with prediabetes

22 Oct 2025 bởi

Eating mangoes daily may help with glycaemic control, insulin sensitivity, and body composition in adults with prediabetes, as shown in a study.

Mangoes serve up metabolic health benefits for adults with prediabetes

22 Oct 2025

What characterizes patients with PTDM?

22 Oct 2025

Patients with post-transplantation diabetes mellitus (PTDM) tend to be older and have higher BMI, triglyceride levels, and hypertension, according to a study.

What characterizes patients with PTDM?

22 Oct 2025

Povorcitinib passes efficacy, safety tests in phase II trial for extensive vitiligo

22 Oct 2025 bởi

Treatment with the Janus kinase (JAK) 1 inhibitor povorcitinib results in significant repigmentation of the body and face in adult patients with extensive nonsegmental vitiligo (NSV), with an acceptable safety profile, through 52 weeks, reports a phase II study.

Povorcitinib passes efficacy, safety tests in phase II trial for extensive vitiligo

22 Oct 2025

CORE model outperforms FIB-4 in predicting liver-related outcomes

22 Oct 2025 bởi

A novel risk score, named Cirrhosis Outcome Risk Estimator (CORE), performs better than FIB-4 in predicting liver-related outcomes in the general population, a study has shown. This model is based on a flexible modelling approach and utilizes biomarkers that are easily accessible in primary care.

CORE model outperforms FIB-4 in predicting liver-related outcomes

22 Oct 2025

Adjuvant cemiplimab prolongs DFS in cutaneous SCC

22 Oct 2025 bởi

In the phase III C-POST trial, adjuvant cemiplimab prolongs disease-free survival (DFS) in individuals at high risk for recurrence of cutaneous squamous cell carcinoma (cSCC).

Adjuvant cemiplimab prolongs DFS in cutaneous SCC

22 Oct 2025

Even low alcohol intake detrimental to East Asian men with MASLD

22 Oct 2025

Intake of even small amounts of alcohol appears to pose a significant health risk for East Asian men with metabolic dysfunction-associated steatotic liver disease (MASLD), according to a South Korean nationwide cohort study.

Even low alcohol intake detrimental to East Asian men with MASLD

22 Oct 2025

Prehabilitation improves surgical outcomes for patients with sarcopenia

21 Oct 2025

A prehabilitation program that integrates exercise and nutritional interventions helps reduce postoperative morbidity in patients with sarcopenia undergoing major liver resection, according to a study.

Prehabilitation improves surgical outcomes for patients with sarcopenia

21 Oct 2025

Ensitrelvir a viable alternative to available antivirals for COVID-19

21 Oct 2025 bởi

The investigational oral antiviral ensitrelvir shows potent antiviral activity in COVID-19, although its effect is slightly weaker than that of ritonavir-boosted nirmatrelvir, according to the ongoing, phase II, randomized controlled, adaptive pharmacometric platform PLATCOV trial.

Ensitrelvir a viable alternative to available antivirals for COVID-19

21 Oct 2025

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Pooled data support ruxolitinib cream for treating prurigo nodularis

Pooled data support ruxolitinib cream for treating prurigo nodularis

Ammoxetine for major depressive disorder clears phase II study

Ammoxetine for major depressive disorder clears phase II study

Mangoes serve up metabolic health benefits for adults with prediabetes

Mangoes serve up metabolic health benefits for adults with prediabetes

What characterizes patients with PTDM?

What characterizes patients with PTDM?

Povorcitinib passes efficacy, safety tests in phase II trial for extensive vitiligo

Povorcitinib passes efficacy, safety tests in phase II trial for extensive vitiligo

CORE model outperforms FIB-4 in predicting liver-related outcomes

CORE model outperforms FIB-4 in predicting liver-related outcomes

Adjuvant cemiplimab prolongs DFS in cutaneous SCC

Adjuvant cemiplimab prolongs DFS in cutaneous SCC

Even low alcohol intake detrimental to East Asian men with MASLD

Even low alcohol intake detrimental to East Asian men with MASLD

Prehabilitation improves surgical outcomes for patients with sarcopenia

Prehabilitation improves surgical outcomes for patients with sarcopenia

Ensitrelvir a viable alternative to available antivirals for COVID-19

Ensitrelvir a viable alternative to available antivirals for COVID-19