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Infliximab, vedolizumab similarly effective as 1L Tx for paediatric IBD
In a study presented at Crohn’s and Colitis Congress 2024, infliximab and vedolizumab were found to have similar effectiveness in achievĀing steroid-free clinical remission (SFCR) and biochemical remission (BR) at 12 months when used as first-line treatment for biologic-naïve paediatric patients with unĀcomplicated mild-to-moderately active inflammatory bowel disease (IBD).
Infliximab, vedolizumab similarly effective as 1L Tx for paediatric IBD
22 Feb 2024Dexmedetomidine use raises body temp in ICU patients with obesity
Critically ill patients with obesity see a significant rise in their body temperature following the use of dexmedetomidine (DEX) for ongoing sedation, as shown in a recent study. Furthermore, DEX duration and baseline temperature are significantly associated with fever development in these individuals.
Dexmedetomidine use raises body temp in ICU patients with obesity
20 Feb 2024Reteplase a good alternative to alteplase in acute ischaemic stroke
Treatment with reteplase appears more effective than alteplase in patients with acute ischaemic stroke (AIS) who have been treated within 4.5 hours of symptom onset, according to the results of RAISE, a phase III multicentre, open-label, randomized controlled, noninferiority trial.
Reteplase a good alternative to alteplase in acute ischaemic stroke
20 Feb 2024Pharmacy model improves drug access, care transition in HF
Implementing a pharmacy practice model consisting of an integrated four-member team (three pharmacists and one specialty technician) leads to better medication access and improved education among heart failure (HF) patients, reports a study. The model also allows for transition of care (ToC) at multiple points in the care process, resulting in enhanced medication safety.
Pharmacy model improves drug access, care transition in HF
20 Feb 2024Earlier anticoagulation reversal tied to improved survival in ICH patients
In anticoagulation-associated intracerebral haemorrhage (ICH), earlier administration of reversal treatments is associated with reduced in-hospital mortality or discharge to hospice, according to data presented at ISC 2024.