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POETYK trials highlight potential of novel drug for plaque psoriasis
The investigational, first-in-class, allosteric tyrosine kinase 2 (TYK2) inhibitor deucravacitinib showed durable efficacy for the treatment of moderate-to-severe plaque psoriasis*, according to the 52-week efficacy analysis results of the POETYK** PSO-1 and POETYK PSO-2 trials presented at EADV 2021.
POETYK trials highlight potential of novel drug for plaque psoriasis
11 Oct 2021Study identifies risk factors for impaired BNT162b2 mRNA antibody response in lupus
Among systemic lupus erythematosus patients, SARS-CoV-2-specific immune responses after BNT162b2 vaccination seem to be impaired in the presence of poor baseline humoral immune status, low naïve B cell frequencies, and mycophenolate mofetil (MMF) and methotrexate (MTX) use, according to a study.
Study identifies risk factors for impaired BNT162b2 mRNA antibody response in lupus
11 Oct 2021Long-term KEEPsAKE data show sustained improvements with risankizumab for PsA
The humanized immunoglobulin G1 monoclonal antibody risankizumab conferred long-term benefit for individuals with active psoriatic arthritis (PsA) who had inadequate responses to biologic and conventional synthetic DMARDs* (csDMARDs), according to the open-label extension (OLE) phase findings of the KEEPsAKE 1 and 2 trials presented at EADV 2021.
Long-term KEEPsAKE data show sustained improvements with risankizumab for PsA
08 Oct 2021Systemic diseases, smoking history linked to more severe dry eye signs
Certain systemic diseases, such as Sjögren syndrome (SS), facial rosacea, rheumatoid arthritis (RA), and peripheral artery disease, and a history of daily cigarette smoking are significantly associated with more severe dry eye disease (DED) signs, a study has found.
Systemic diseases, smoking history linked to more severe dry eye signs
07 Oct 2021Retinal thinning may foreshadow neurodegeneration in SLE
Patients with systemic lupus erythematosus (SLE) show progressive reduction in the thickness of peripapillary retinal nerve fibre layer, suggestive of early neurodegeneration, a recent study has found.
Retinal thinning may foreshadow neurodegeneration in SLE
02 Oct 2021Osteopathy prevalent among patients with chronic pancreatitis
Majority of patients with chronic pancreatitis also have osteoporosis or osteopenia, with risk factors including older age and lower body mass index, among others, according to a study.
Osteopathy prevalent among patients with chronic pancreatitis
30 Sep 2021Romosozumab prevents new vertebral fractures in postmenopausal women with osteoporosis
Twelve months of treatment with romosozumab produce marked reductions in new vertebral fractures, especially moderate-to-severe fractures, among postmenopausal women with osteoporosis, according to a study.