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Niraparib-abiraterone-prednisone combo improves multiple outcomes in HRR+ mCRPC
In patients with metastatic castration-resistant prostate cancer (mCRPC) with homologous recombination repair (HRR) gene alterations*, combining niraparib with abiraterone acetate plus prednisone (AAP) in the first-line setting improved radiographic progression-free survival (rPFS) and other outcomes, results of the phase III MAGNITUDE study showed.
Niraparib-abiraterone-prednisone combo improves multiple outcomes in HRR+ mCRPC
04 Mar 2022High-dose ipilimumab augments nivolumab benefit for TCC
In the phase II TITAN-TCC* trial presented at ASCO GU 2022, the addition of ipilimumab to nivolumab led to improved responses in patients with pretreated (second/third line) advanced/metastatic or surgically unresectable transitional cell carcinoma (TCC).
High-dose ipilimumab augments nivolumab benefit for TCC
01 Mar 2022Avelumab continues to show promise for bladder cancer
In individuals with advanced urothelial carcinoma (UC), a first-line maintenance treatment regimen comprising a combination of avelumab and best supportive care (BSC) provided better survival benefit than BSC alone, according to long-term and subgroup analyses of the phase III JAVELIN Bladder 100 trial presented at ASCO GU 2022.
Avelumab continues to show promise for bladder cancer
28 Feb 2022Risk downgrade common in GGG3 prostate cancer patients with single positive biopsy core
In Gleason grade group (GGG) 3 prostate cancer patients with a single intermediate-risk positive biopsy core, risk downgrading appears to be more likely than upgrading, reports a new study.
Risk downgrade common in GGG3 prostate cancer patients with single positive biopsy core
13 Feb 2022Which factor impels offering of postoperative chemotherapy in nonmuscle invasive bladder cancer?
A recent study has shown clear preferences by urologists when providing postoperative immediate chemotherapy in nonmuscle invasive bladder cancer (NMIBC). Factors beyond clinical variables, such as the structure of the recovery room, play a role in this decision-making process.