Tin tức & Cập nhật

Treatment with the oral Toll-like receptor 8 (TLR8) agonist selgantolimod once weekly for 24 weeks is well tolerated and generally safe in patients with chronic hepatitis B (CHB) under viral suppression, according to a recent study.

Early treatment with a single dose of pegylated recombinant IL-29 type III interferon (IFN), otherwise known as peg lambda, significantly reduced clinical events in the phase III TOGETHER study evaluating mostly vaccinated, acutely symptomatic COVID-19 outpatients.

Pregnant women who contract COVID-19 during early and mid-pregnancy are at risk of stillbirth, but this risk may not be present when infection occurs at any time during the third trimester or before delivery, as reported in a study.

A real-world study during Hong Kong’s Omicron BA.2.2 wave has shown that viral burden rebound is uncommon in hospitalized COVID-19 patients not requiring supplemental oxygen on admission, regardless of whether they were treated with nirmatrelvir/ritonavir or molnupiravir. However, immunocompromised patients, regardless of oral antiviral use, are more likely to have viral burden rebound.

Human papillomavirus (HPV) infection appears to be a risk factor for cardiovascular diseases (CVDs), suggests a recent study. However, women vaccinated against HPV are protected against such risk.

Use of doxycycline as postexposure prophylaxis (PEP) results in a significant decrease in the incidence of Chlamydia trachomatis (CT) and syphilis and demonstrates a significant impact on the incidence of Neisseria gonorrhoeae (GC), reports a study presented at the 30th Conference on Retroviruses and Opportunistic Infections (CROI). Meningococcal B vaccine also helps lower the incidence of GC.

The incidence of sexually transmitted infection (STI) over the first 4 years of pre-exposure prophylaxis (PrEP) use remains high and stable, but the incidence of chlamydia and gonorrhea has slightly decreased among daily PrEP users, as shown in a study presented at the 30th Conference on Retroviruses and Opportunistic Infections (CROI).

Patients with inflammatory bowel disease (IBD) who undergo foecal microbiota transplantation (FMT) are less likely to develop recurrent Clostridioides difficile infection (CDI), a study has shown.