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Treatment with amantadine appears to lower mortality among COVID-19 patients with severe respiratory failure in the intensive care unit (ICU), a retrospective study has found.

Amantadine confers survival benefits on ICU patients with severe COVID-19

MACE risk higher with tofacitinib vs TNFi in patients with RA, ASCVD

In the treatment of patients with rheumatoid arthritis (RA) and atherosclerotic cardiovascular disease (ASCVD), the use of tofacitinib confers an increased risk of major adverse cardiovascular events (MACE) than tumour necrosis factor inhibitors (TNFi), according to a post hoc analysis of ORAL Surveillance.

MACE risk higher with tofacitinib vs TNFi in patients with RA, ASCVD

Telepsychiatry as reliable as face-to-face interviews for symptom assessment

29 Sep 2022 bởi

Assessments of depressive, anxiety and psychotic symptoms and suicidal risk by telepsychiatry have good reliability in general when compared with face-to-face interviews, according to researchers from the Queen Mary Hospital (QMH).

Telepsychiatry as reliable as face-to-face interviews for symptom assessment

29 Sep 2022

Adjuvant pembrolizumab continues to improve DFS in clear cell RCC

In patients with clear cell renal cell carcinoma (RCC), adjuvant pembrolizumab continues to improve disease-free survival (DFS) over placebo, according to extended follow-up of the phase III KEYNOTE-564 trial.

Adjuvant pembrolizumab continues to improve DFS in clear cell RCC

28 Sep 2022

Multiple-dose antibiotic not recommended for preventing infection after breast reconstruction

The use of multiple-dose antibiotic to prevent surgical site infection and implant removal following implant-based breast reconstruction does not appear to be more effective than a single-dose regimen, as shown in a study. In addition, the multi-dose regimen increases the risk of adverse events associated with antibiotic treatment.

Multiple-dose antibiotic not recommended for preventing infection after breast reconstruction

Tiny implantable cooling device promises drug-free pain relief

A soft, miniaturized bioresorbable implant that delivers focused, minimally invasive cooling power in living tissues can help alleviate pain on demand without the use of medications and may provide an alternative to opioids and other highly addictive painkillers.

Tiny implantable cooling device promises drug-free pain relief

Tumour volume predicts pathologic complete response in rectal cancer patients

In locally advanced rectal cancer patients on neoadjuvant chemoradiation, a tumour volume threshold of 37.3 cm3 is associated with pathologic complete response (pCR), suggests a recent study.

Tumour volume predicts pathologic complete response in rectal cancer patients

Vision impairment tied to depression, anxiety in children

Children with vision impairment are at higher risk of developing symptoms of depression and anxiety, according to a study, noting that surgical treatment of strabismus may improve these symptoms.

Vision impairment tied to depression, anxiety in children

28 Sep 2022

Active surveillance with delayed intervention a safe, cheaper option for small renal masses

Active surveillance (AS) along with timely delayed intervention (DI) is a safe and economical alternative to immediate intervention in patients with small renal masses (SRM), suggests a study.

Active surveillance with delayed intervention a safe, cheaper option for small renal masses

FINLAY-FR-1A vaccine boosts natural immunity in COVID-19 convalescents