Tin tức & Cập nhật

Adjuvant dabrafenib-trametinib confers durable RFS benefit for resected stage III melanoma

03 Dec 2020 bởi

Adjuvant therapy with the BRAF inhibitor dabrafenib and the MEK inhibitor trametinib for 12 months led to long-term relapse-free survival (RFS) with no apparent long-term toxicities in patients with resected stage III melanoma with BRAF V600E or V600K mutations, according to the extended follow-up results of the phase III COMBI-AD* trial.

Adjuvant dabrafenib-trametinib confers durable RFS benefit for resected stage III melanoma

03 Dec 2020

COVID-19 patients exhale millions of virus in early stages

02 Dec 2020 bởi

COVID-19 patients carry particularly high viral loads during the early stages of the disease, with millions of virus exhaled in their breath per hour, reveals a study — which indicates that breath emission could possibly contribute to airborne transmission of the virus.

COVID-19 patients exhale millions of virus in early stages

02 Dec 2020

Concurrent vasopressor, nephrotoxic agents up risk of AKI in critically ill youths on vancomycin

02 Dec 2020

Nearly half of critically ill adolescent and young adult patients who received vancomycin develop acute kidney injury (AKI), according to a study.

Concurrent vasopressor, nephrotoxic agents up risk of AKI in critically ill youths on vancomycin

02 Dec 2020

Crushed prasugrel offers no reperfusion benefit prior to PCI

02 Dec 2020 bởi

Giving crushed prasugrel to patients with ST-segment elevation myocardial infarction (STEMI) en route to the hospital for planned PCI* does not improve reperfusion rates compared with giving the tablets whole in the COMPARE CRUSH trial.

Crushed prasugrel offers no reperfusion benefit prior to PCI

02 Dec 2020

VP-102 shows potential in treating molluscum contagiosum

02 Dec 2020 bởi

VP-102, a proprietary, drug-device combination containing cantharidin 0.7% (w/v), was effective and safe for treating molluscum contagiosum (MC), according to the phase III CAMP* trials.

VP-102 shows potential in treating molluscum contagiosum

02 Dec 2020

Original New Drug Application Approvals by US FDA (16 - 30 November 2020)

02 Dec 2020

New drug applications approved by US FDA as of 16 - 30 November 2020 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16 - 30 November 2020)

02 Dec 2020

Alzheimer’s disease prevention: Can antidepressants lend a hand?

01 Dec 2020 bởi

The selective serotonin reuptake inhibitor escitalopram holds promise in the prevention of Alzheimer’s disease, reducing amyloid-β-42 levels in cerebrospinal fluid and brain tissue in older adults with normal cognitive function, according to recent evidence.

Alzheimer’s disease prevention: Can antidepressants lend a hand?

01 Dec 2020

Gabapentin ineffective for chronic pelvic pain in women

30 Nov 2020 bởi

A daily dose of gabapentin does not appear effective in reducing chronic pelvic pain in women, according to results of the GaPP2 study from the UK.

Gabapentin ineffective for chronic pelvic pain in women

30 Nov 2020

Anlotinib a new treatment alternative for thyroid cancer?

30 Nov 2020 bởi

Anlotinib demonstrated high survival benefit and treatment response rates in patients with locally advanced and metastatic radio-iodine-refractory differentiated thyroid carcinoma (RAIR-DTC), a phase II study from China has shown.

Anlotinib a new treatment alternative for thyroid cancer?

30 Nov 2020

Regional citrate trumps systemic heparin for dialysis filter

28 Nov 2020 bởi

Using regional citrate for anticoagulation during dialysis significantly extends the lifespan of dialysis filter compared with systemic heparin anticoagulation, although this has no impact on the patients’ mortality rate over 1 year, according to the RICH study presented at ASN 2020.

Regional citrate trumps systemic heparin for dialysis filter

28 Nov 2020

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Adjuvant dabrafenib-trametinib confers durable RFS benefit for resected stage III melanoma

Adjuvant dabrafenib-trametinib confers durable RFS benefit for resected stage III melanoma

COVID-19 patients exhale millions of virus in early stages

COVID-19 patients exhale millions of virus in early stages

Concurrent vasopressor, nephrotoxic agents up risk of AKI in critically ill youths on vancomycin

Concurrent vasopressor, nephrotoxic agents up risk of AKI in critically ill youths on vancomycin

Crushed prasugrel offers no reperfusion benefit prior to PCI

Crushed prasugrel offers no reperfusion benefit prior to PCI

VP-102 shows potential in treating molluscum contagiosum

VP-102 shows potential in treating molluscum contagiosum

Original New Drug Application Approvals by US FDA (16 - 30 November 2020)

Original New Drug Application Approvals by US FDA (16 - 30 November 2020)

Alzheimer’s disease prevention: Can antidepressants lend a hand?

Alzheimer’s disease prevention: Can antidepressants lend a hand?

Gabapentin ineffective for chronic pelvic pain in women

Gabapentin ineffective for chronic pelvic pain in women

Anlotinib a new treatment alternative for thyroid cancer?

Anlotinib a new treatment alternative for thyroid cancer?

Regional citrate trumps systemic heparin for dialysis filter

Regional citrate trumps systemic heparin for dialysis filter