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Linezolid flops against benzathine penicillin G for early syphilis
In the treatment of patients with early syphilis, a 5-day course of linezolid does not appear to perform as well as the standard of care benzathine penicillin G (BPG), as shown in a study.
Linezolid flops against benzathine penicillin G for early syphilis
12 Jan 2024Add-on carfilzomib yields benefits in transplant-ineligible NDMM patients
The addition of carfilzomib to lenalidomide and dexamethasone (KRd) improved outcomes in individuals with newly diagnosed fit or intermediate-fit multiple myeloma who are transplant ineligible (NTE NDMM) as opposed to Rd only in the phase III EMN20 trial.
Add-on carfilzomib yields benefits in transplant-ineligible NDMM patients
10 Jan 2024Capivasertib-fulvestrant improves life quality in advanced breast cancer
The addition of capivasertib (C) to fulvestrant (F) results in better health-related quality of life (HRQoL), except for diarrhoea, in patients with aromatase inhibitor-resistant HR-positive/HER2-negative advanced breast cancer when compared to placebo plus F, according to the phase III CAPItello-291 study presented at SABCS 2023.
Capivasertib-fulvestrant improves life quality in advanced breast cancer
09 Jan 2024BMI prognostic of adjuvant chemo potency in breast cancer
Body mass index (BMI) has some bearing on the efficacy of different adjuvant chemotherapy schedules in patients with early breast cancer, suggest the results of the GIM2 study, which were presented at the recent SABCS 2023. Additionally, dose-dense (DD) chemotherapy appears to be the better treatment strategy regardless of a patient’s BMI.
BMI prognostic of adjuvant chemo potency in breast cancer
09 Jan 2024mRNA boosters protect cancer patients against adverse COVID-19 outcomes
A prospective study from Singapore provides evidence of the clinical effectiveness of mRNA-based vaccines against COVID-19 in individuals with cancer.