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Adagrasib shows antitumour activity in KRAS G12C-mutant colorectal cancer
Adagrasib appears to have some effect against metastatic, KRAS G12C-mutated colorectal cancer when used in treatment-experienced patients either as oral monotherapy or in combination with cetuximab, according to the results of a phase I-II, open-label study.
Adagrasib shows antitumour activity in KRAS G12C-mutant colorectal cancer
07 Jan 2023
Investigational antisense oligonucleotide for chronic HBV infection shows positive results
Treatment with the antisense oligonucleotide bepirovirsen appears to lead to sustained loss of hepatitis B surface antigen (HBsAg) and hepatitis B virus (HBV) DNA in up to 10 percent of patients with chronic HBV infection, according to the results of the phase IIb study B-Clear.
Investigational antisense oligonucleotide for chronic HBV infection shows positive results
06 Jan 2023
Procalcitonin-based algorithm reduces unnecessary antibiotic use in acute pancreatitis
A procalcitonin-guided algorithm could reduce the unnecessary use of antibiotics in patients with acute pancreatitis, according to results of the PROCAP trial.
Procalcitonin-based algorithm reduces unnecessary antibiotic use in acute pancreatitis
01 Jan 2023
Coeliac disease tied to higher risk of juvenile idiopathic, rheumatoid arthritis
Young patients with coeliac disease (CD) tend to develop juvenile idiopathic arthritis (JIA) three times more often than does the general population, while adult CD patients appear to have rheumatoid arthritis (RA) nearly twice as often, reveals a study.
Coeliac disease tied to higher risk of juvenile idiopathic, rheumatoid arthritis
26 Dec 2022
FMT offers no weight loss benefits in individuals with obesity
For individuals with obesity who are scheduled to undergo bariatric surgery, faecal microbiota transplantation (FMT) from a lean donor does not appear to help reduce weight before or after the procedure, according to a study.
FMT offers no weight loss benefits in individuals with obesity
22 Dec 2022
Bepirovirsen shows promise in controlling chronic HBV infection
Weekly bepirovirsen treatment may help reduce HBsAg* and hepatitis B virus (HBV) DNA levels in patients with chronic HBV infection, the phase IIb B-Clear study showed.
Bepirovirsen shows promise in controlling chronic HBV infection
19 Dec 2022
Noninvasive approach useful for detecting postoperative recurrence in Crohn’s disease
A noninvasive diagnostic approach that combines bowel ultrasound and faecal calprotectin test appears to be reliable for detecting disease recurrence in Crohn’s disease (CD) patients who have undergone ileo-cecal resection, according to a study.