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Nonchemotherapy doublet shows therapeutic potential in PD-1/PD-L1 inhibitor‒resistant NSCLC
Combination treatment with eftilagimod alpha plus pembrolizumab has shown promising signal of activity against metastatic nonsmall cell lung cancer (NSCLC) in patients resistant to PD-1/PD-L1 inhibitors, as shown in the updated results of the phase II TACTI-002 study.
Nonchemotherapy doublet shows therapeutic potential in PD-1/PD-L1 inhibitor‒resistant NSCLC
09 Jun 2023Pazopanib plus chemo improves response but not survival in advanced ovarian cancer
Treatment with pazopanib combined with chemotherapy leads to better overall response rate (ORR) in patients with recurrent or persistent ovarian cancer but falls short of improving survival, reveals a study. In addition, the combination therapy contributes to an increase in several adverse events (AEs).
Pazopanib plus chemo improves response but not survival in advanced ovarian cancer
08 Jun 2023First-line cemiplimab improves survival in unresectable NSCLC
First-line treatment with cemiplimab, either as monotherapy or in combination with platinum-based chemotherapy, provides clinical benefits to patients with unresectable locally advanced nonsmall cell lung cancer (NSCLC) who are not candidates for definitive concurrent chemoradiation, as shown by long-term follow-up data from EMPOWER-Lung studies.
First-line cemiplimab improves survival in unresectable NSCLC
08 Jun 2023Psychedelic drugs show promise for anxiety, depression
Use of psychedelic drugs appears to have some benefits in reducing anxiety and depressive symptoms among patients with cancer or other life-threatening diseases, reports a study.
Psychedelic drugs show promise for anxiety, depression
08 Jun 2023Is liposomal irinotecan superior to topotecan in relapsed small cell lung cancer?
Treatment with liposomal irinotecan in adults with relapsed small cell lung cancer (SCLC) achieves similar overall survival (OS) when compared with topotecan, but the former is associated with a higher overall response rate (ORR), according to the results of RESILIENT, randomized, open-label phase III trial.
Is liposomal irinotecan superior to topotecan in relapsed small cell lung cancer?
07 Jun 2023Does extended lymph node sampling increase complications?
Patients undergoing more extensive lymph node sampling during surgery for a suspected malignant paediatric renal tumour do not appear to have a higher likelihood of experiencing clinically significant complications, reveals a study.
Does extended lymph node sampling increase complications?
06 Jun 2023Nivolumab-chemo poised to alter NSCLC treatment landscape
In the 3-year analysis of the phase III CheckMate 816 trial, neoadjuvant nivolumab plus platinum doublet chemotherapy (nivo-chemo) continued to provide durable benefit for individuals with resectable non-small-cell lung cancer (NSCLC).