Tin tức & Cập nhật

Treatment with the combination of ribociclib plus binimetinib appears to be well tolerated and delivers modest clinical activity in patients with locally advanced or metastatic melanoma harbouring NRAS mutation, according to the results of a phase Ib/II study.

Salivary levels of the inflammatory biomarker immunoglobulin A (IgA) appear to be significantly suppressed in type 1 diabetes mellitus (DM) patients with neuropathy (DMN), reports a recent study.

A novel nitric oxide-releasing gel, berdazimer 10.3%, proves effective in the treatment of patients with water warts or molluscum contagiosum skin infection, facilitating clearance of lesions with low adverse event rates, as shown in the phase III B-SIMPLE4 trial.

Individuals with resistant hypertension who undergo lifestyle modification have better cognitive function, and this benefit may be attributed to the reduced ambulatory systolic blood pressure (SBP) changes through weight loss, suggests a study.

Real-world patients with psoriatic arthritis (PsA) who received and remained on secukinumab treatment for 6 months has attained minimal disease activity (MDA) and shown improvements in clinical manifestations, patient-reported outcomes, and work productivity at follow-up, reveals a study. The results are consistent with findings from clinical trials.

Several factors, including older age, overnight emergency department (ED) arrival time, higher serum urate (SU), higher C-reactive protein (CRP), and higher total white cell count at presentation, predict hospitalization for acute gout, according to a study.

Only pre-eclampsia, among other hypertensive disorders of pregnancy, contributes to a higher risk of nonsyndromic orofacial clefts (NSOFCs) and its subtypes, a study has found.