Tin tức & Cập nhật

Upadacitinib outdoes abatacept for rheumatoid arthritis

14 Dec 2020 bởi

The oral selective Janus kinase (JAK) inhibitor upadacitinib was superior to IV abatacept, a T-cell costimulation modulator, for the treatment of rheumatoid arthritis (RA) that is refractory to biologic disease-modifying antirheumatic drugs (bDMARDs), the SELECT-CHOICE trial has shown.

Upadacitinib outdoes abatacept for rheumatoid arthritis

14 Dec 2020

Risankizumab trumps ustekinumab, placebo for moderate-to-severe psoriasis

10 Dec 2020 bởi

The novel, humanized IgG1 monoclonal antibody risankizumab was superior to ustekinumab and placebo in reducing and potentially eliminating symptoms of moderate-to-severe chronic plaque psoriasis, according to two replicate phase III trials.

Risankizumab trumps ustekinumab, placebo for moderate-to-severe psoriasis

10 Dec 2020

Tocilizumab strikes out in hand osteoarthritis

10 Dec 2020

Interleukin (IL)-6 blockade with tocilizumab is only as good as placebo at easing pain in patients with hand osteoarthritis, a study has found.

Tocilizumab strikes out in hand osteoarthritis

10 Dec 2020

Dehydroepiandrosterone boosts QoL of premenopausal RA patients

21 Oct 2020

Dehydroepiandrosterone supplementation confers benefits for quality of life (QoL) but not for disease activity relative to placebo in premenopausal women with rheumatoid arthritis (RA), a study has found.

Dehydroepiandrosterone boosts QoL of premenopausal RA patients

21 Oct 2020

Seletalisib shows therapeutic potential in primary Sjögren’s syndrome

19 Oct 2020

The selective PI3Kδ inhibitor seletalisib demonstrates clinical activity in patients with primary Sjögren’s syndrome (PSS) despite enrolment-related underpowering, as shown in phase II trial data.

Seletalisib shows therapeutic potential in primary Sjögren’s syndrome

19 Oct 2020

TNFi safe, effective in reactive arthritis, but treatment tends to be long

16 Oct 2020

Although treatment with tumour necrosis factor inhibitors (TNFi) tends to be prolonged, it has been shown to be safe and effective in reactive arthritis (ReA), according to a study.

TNFi safe, effective in reactive arthritis, but treatment tends to be long

16 Oct 2020

Big waist ups low physical function risk in adults with knee OA

15 Oct 2020

A growing waistline increases the risk of incident low physical function in the following year among adults with knee osteoarthritis (OA), suggests a recent study. Maintaining waist circumference (WC) may prevent the development of low physical function.

Big waist ups low physical function risk in adults with knee OA

15 Oct 2020

Romilkimab delivers in diffuse cutaneous systemic sclerosis

15 Oct 2020

Romilkimab, a novel bispecific immunoglobulin-G4 antibody that binds and neutralizes interleukin (IL)-4/IL-13, shows promise in the treatment of diffuse cutaneous systemic sclerosis, producing significant reduction in skin fibrosis, according to the results of a phase II trial.

Romilkimab delivers in diffuse cutaneous systemic sclerosis

15 Oct 2020

Activity trackers a promising way to predict gout flares

14 Oct 2020 bởi

Wearable activity trackers are feasible for collecting data on physical activity patterns that may be used to estimate gout flares, as shown in a study.

Activity trackers a promising way to predict gout flares

14 Oct 2020

Cigarette smoking ups systemic lupus erythematosus risk

14 Oct 2020

Smoking cigarettes appears to increase the risk of systemic lupus erythematosus (SLE), suggests a recent study. In addition, sex and age do not contribute to the risk of SLE over time.

Cigarette smoking ups systemic lupus erythematosus risk

14 Oct 2020

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Upadacitinib outdoes abatacept for rheumatoid arthritis

Upadacitinib outdoes abatacept for rheumatoid arthritis

Risankizumab trumps ustekinumab, placebo for moderate-to-severe psoriasis

Risankizumab trumps ustekinumab, placebo for moderate-to-severe psoriasis

Tocilizumab strikes out in hand osteoarthritis

Tocilizumab strikes out in hand osteoarthritis

Dehydroepiandrosterone boosts QoL of premenopausal RA patients

Dehydroepiandrosterone boosts QoL of premenopausal RA patients

Seletalisib shows therapeutic potential in primary Sjögren’s syndrome

Seletalisib shows therapeutic potential in primary Sjögren’s syndrome

TNFi safe, effective in reactive arthritis, but treatment tends to be long

TNFi safe, effective in reactive arthritis, but treatment tends to be long

Big waist ups low physical function risk in adults with knee OA

Big waist ups low physical function risk in adults with knee OA

Romilkimab delivers in diffuse cutaneous systemic sclerosis

Romilkimab delivers in diffuse cutaneous systemic sclerosis

Activity trackers a promising way to predict gout flares

Activity trackers a promising way to predict gout flares

Cigarette smoking ups systemic lupus erythematosus risk

Cigarette smoking ups systemic lupus erythematosus risk