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Female gender, dosage predict gastrin elevation in GERD patients on long-term PPI therapy

Dosage and female gender are associated with the development of gastrin elevation following proton pump inhibitor (PPI) therapy, a recent study has found. Moreover, fasting serum gastrin significantly correlates with PPI dosage over weight and over body surface area.

Female gender, dosage predict gastrin elevation in GERD patients on long-term PPI therapy

Pharmacist intervention reduces prescribing errors of investigational drugs in cancer clinical trials

13 Feb 2020 bởi

A pharmacist intervention appears to be effective in lowering and preventing the incidence of prescribing errors of investigational drugs in oncology clinical trials, a recent study has shown.

Pharmacist intervention reduces prescribing errors of investigational drugs in cancer clinical trials

Off-label dupilumab safe, effective for atopic dermatitis in kids

Off-label dupilumab shows potential in the treatment of atopic dermatitis (AD) in children, although appropriate dosing recommendations have yet to be established, suggests a new study.

Off-label dupilumab safe, effective for atopic dermatitis in kids

Vedolizumab matches infliximab in controlling arthralgias in IBD

Vedolizumab was similarly effective as infliximab in the control of arthralgias in patients with inflammatory bowel disease (IBD) in the real world, suggests a head-to-head study presented at the Crohn's & Colitis Congress (CCC) 2020.

Vedolizumab matches infliximab in controlling arthralgias in IBD

No link between anti-TNF agents and lymphoma in paediatric IBD

Children with inflammatory bowel disease (IBD) do not appear to have an elevated risk of lymphoma following treatment with anti-tumour necrosis factor (TNF) agents, according to a study presented at the recent Crohn’s and Colitis Congress 2020.

No link between anti-TNF agents and lymphoma in paediatric IBD

Timely treatment of GI symptoms leads to effective management of AS patients on NSAIDs

Timely therapeutic strategies appear to effectively manage gastrointestinal (GI) risk in ankylosing spondylitis (AS) patients undergoing treatment with nonsteroidal anti-inflammatory drugs (NSAIDs), as shown in a recent study.

Timely treatment of GI symptoms leads to effective management of AS patients on NSAIDs

Alternative sunitinib dosing regimens prolong survival in metastatic renal cell carcinoma

Alternative dosing regimens of sunitinib appear to be effective in improving survival outcomes of patients with metastatic renal cell carcinoma (MRCC), results of a study have shown.

Alternative sunitinib dosing regimens prolong survival in metastatic renal cell carcinoma

Fenfluramine: potential new label for rare type of epilepsy?

The amphetamine derivative fenfluramine, previously marketed as an appetite suppressant to manage obesity, delivers a different promise in a new phase III trial by showing its anti-epileptic potential in children and young adults with Dravet syndrome.

Fenfluramine: potential new label for rare type of epilepsy?

R-CHOP reduction: A paradigm shift in B-NHL?

Four cycles of the chemotherapeutic regimen comprising cyclophosphamide, doxorubicin, vincristine, and prednisone plus six cycles of rituximab (R-CHOP) are noninferior to the standard six cycles of R-CHOP for the treatment of B-cell non-Hodgkin lymphoma (B-NHL) in young patients (≤60 years) with a favourable risk profile, the FLYER trial shows.

R-CHOP reduction: A paradigm shift in B-NHL?