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When used in addition to standard of care, favipiravir leads to faster viral clearance and clinical improvement time among patients hospitalized with COVID-19, although it appears to contribute to an increased risk of hyperuricaemia, according to the results of a meta-analysis

Add-on favipiravir brightens outlook for hospitalized COVID-19 patients

06 May 2022

Residential noise can take toll on mental health

Exposure to noise, particularly in residential areas, appears to have negative consequences on mental health, as reported in a study.

Residential noise can take toll on mental health

Adebrelimab plus chemo almost doubles OS, triples PFS in extensive-stage SCLC

06 May 2022 bởi

Adding adebrelimab to chemotherapy improves survival outcomes over chemotherapy alone in patients with extensive-stage small cell lung cancer (SCLC) in the phase III CAPSTONE-1 study presented at AACR 2022. This brings hope to SCLC patients with limited treatment options and poor prognoses.

Adebrelimab plus chemo almost doubles OS, triples PFS in extensive-stage SCLC

Open surgery a better option than minimally invasive hysterectomy in early cervical cancer?

Undergoing a minimally invasive radical hysterectomy leads to worse survival outcomes compared with open surgery in patients with early cervical cancer, according to final results of the LACC trial presented at SGO 2022.

Open surgery a better option than minimally invasive hysterectomy in early cervical cancer?

05 May 2022

UWFA detects more retinal capillary nonperfusion in temporal quadrant

Ultra-widefield angiography (UWFA) is able to identify more retinal capillary nonperfusion (RCNP) than conventional fundus fluorescein angiography, particularly in the temporal quadrant. Of note, large increases in RCNP over 100 weeks of follow-up seeme to be uncommon.

UWFA detects more retinal capillary nonperfusion in temporal quadrant

Adding durvalumab upfront to chemo ups long-term survival in SCLC

Patients were threefold more likely to survive long term (beyond 3 years) when durvalumab was added to first-line chemotherapy, with or without tremelimumab, compared with those on chemotherapy alone, according to a post hoc analysis of long-term survivors (LTS) with extensive-stage small-cell lung cancer (ES-SCLC) in the CASPIAN study.

Adding durvalumab upfront to chemo ups long-term survival in SCLC

Physical pain highly prevalent among patients with psychiatric illness

Most patients with psychiatric illness sustain physical pain, and they perceive pain differently, according to a Singapore study.

Physical pain highly prevalent among patients with psychiatric illness

Viruses causing gastroenteritis in children thrive in stools of asymptomatic carriers

The stools of asymptomatic patients carry the most common viruses that cause gastroenteritis in children and serve as a potential reservoir for acute gastroenteritis (AGE), a study has shown.

Viruses causing gastroenteritis in children thrive in stools of asymptomatic carriers

05 May 2022

When is the best time to initiate peritoneal dialysis in ESKD patients?

A planned start appears to be the best strategy for initiating peritoneal dialysis (PD) in patients with end-stage kidney disease (ESKD), but an early start is a good alternative if a planned start is not possible, suggests a Singapore study. In addition, catheter migration may be more frequent with early-start PD, but it does not seem to affect technique survival.

When is the best time to initiate peritoneal dialysis in ESKD patients?

Which agent is safe, most effective for treating cutaneous polyarteritis nodosa?

Use of colchicine provides a good balance between benefit and risk in patients with cutaneous polyarteritis nodosa without peripheral sensory neuropathy, reports a study. In the event of relapse, the best treatment appears to be the combination of glucocorticoids and azathioprine.

Which agent is safe, most effective for treating cutaneous polyarteritis nodosa?