Tin tức & Cập nhật

Patients with moderate or severe mitral regurgitation who have been admitted for heart failure exacerbation or has an elevated right atrial pressure, renal dysfunction, anaemia, or lacks a mitral valve intervention suffer a greater risk of all-cause mortality, reveals a study.

Most patients with inflammatory bowel disease (IBD) build an initial immune response to SARS-CoV-2 vaccination, but older patients, those treated with antitumour necrosis factor (anti-TNF) and an immunomodulator, and those on corticosteroids may require an additional vaccine dose to achieve better immunity against COVID-19, according to a study.

Use of oral antibiotics in the treatment of osteomyelitis, bacteraemia, and infective endocarditis results in shorter hospital stay, has a better safety profile, and appears to be similarly effective when compared to intravenous (IV)-only therapy, a recent study has shown.

Rescue therapy using the Janus kinase 1 inhibitor abrocitinib combined with topical medicated therapy recaptured efficacy responses and had a favourable safety profile in individuals with moderate-to-severe atopic dermatitis (AD) who experienced flare during the maintenance period of the phase III randomized-withdrawal JADE REGIMEN trial.

Strong family resilience may help lessen the psychological consequences of the coronavirus disease 2019 (COVID-19), according to a recent Singapore study.

Treatment with intravenous brivaracetam is well tolerated in children with epilepsy, with a safety profile consistent with that known of the oral formulation, according to the results of a phase II study. There has been no pharmacokinetic difference observed when administered as bolus or a 15-minute infusion.

The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is more stable than the ancestral strain on various smooth and porous surfaces and demonstrates marked resistance to neutralizing monoclonal antibodies (mAbs), researchers from the University of Hong Kong (HKU) have reported.

Eating fish can reduce the risk of stroke, but the benefit is dictated by how fish is prepared and how often it is consumed, according to a study. Specifically, frequent consumption of baked or broiled fish is protective while regular consumption of fried fish contributes to a risk increase, which differs by socioeconomic status.