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Novel meningitis/encephalitis CSF testing shortens antiviral prescribing duration
The duration of antiviral prescribing has become much shorter with the introduction of the Biofire Filmarray meningitis/encephalitis (M/E) panel, a study has shown. However, its influence on antibiotic prescribing or health services in a paediatric hospital is minimal.
Weight loss in early adulthood delays biological ageing
Weight gain among adults appears to speed up a person’s biological age, with a recent study showing the associations of maximal overweight, nonobese to obese, and stable obesity across adulthood with accelerated biological ageing. On the other hand, weight loss from young to middle adulthood tends to slow down biological ageing.
C3 levels tied to incident T2DM; BMI plays a mediating role
Complement C3 levels may be used as a predictor of incident type 2 diabetes mellitus (T2DM), suggests a study. In addition, body mass index (BMI) may have a mediating role in the association between C3 and T2DM, offering clues for diabetes pathogenesis.
Cyclophosphamide-free adjuvant chemo works against ERBB2-negative breast cancer
The adjuvant chemotherapy regimen epirubicin plus paclitaxel (EP) appears to be as good as the regimen that consists of epirubicin and cyclophosphamide followed by paclitaxel (EC-P) in the treatment of Asian women with operable ERBB2-negative breast cancer, according to the results of an open-label phase III trial.
Pituitary-targeting seliciclib shows promise in treatment of Cushing disease
In a recent study, seliciclib therapy demonstrates its potential in reversing hypercortisolism by directly targeting pituitary corticotrophs in Cushing disease (CD). However, the agent is associated with liver toxicity, which is resolved by withdrawing treatment.
