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Real-world COPD treatment practices in SG lag behind updated guidelines
Many patients with chronic obstructive pulmonary disease (COPD) in Singapore could benefit from treatment escalation under the latest Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines, as reported by a group of researchers.
Real-world COPD treatment practices in SG lag behind updated guidelines
02 Apr 2024Bevacizumab + EGFR-TKI improves OS in EGFR-mutated NSCLC with leptomeningeal metastases
Adding bevacizumab to an EGFR tyrosine kinase inhibitor (TKI) improves overall survival (OS) in adult patients with EGFR-mutated non-small-cell lung cancer (NSCLC) and leptomeningeal metastases (LMs), according to a single-centre, retrospective, real-world study in China. OS was, however, similar between patients on chemotherapy plus EGFR-TKI and those on EGFR-TKI monotherapy.
Bevacizumab + EGFR-TKI improves OS in EGFR-mutated NSCLC with leptomeningeal metastases
20 Mar 2024Broaden screening in patients with TB or HBV, says study
Patients with hepatitis B virus (HBV) infection are at heightened risk of latent tuberculosis (TB), while those with latent TB are also at increased risk of HBV infection, reveals a study. Notably, the risk of co-infection is highest among Asians and those born in high-incidence countries.
Broaden screening in patients with TB or HBV, says study
17 Mar 2024Negative mood worsens dyspnoea in COPD
A negative affective state can aggravate dyspnoea in patients with chronic obstructive pulmonary disease (COPD), a study has shown. This suggests that reducing the likelihood of negative mood or improving the mood can help in managing morbidities associated with dyspnoea in COPD.
Negative mood worsens dyspnoea in COPD
10 Mar 2024Severe COVID-19 rare in PrEP-treated SARDs patients
Breakthrough COVID-19 is not uncommon following pre-exposure prophylaxis (PrEP) with tixagevimab/cilgavimab among patients with systemic autoimmune rheumatic diseases (SARDs), reports a recent study. However, most of the infections in this high-risk population are not severe.