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People who spend long hours (>4 hours a day) watching television (TV) have an increased risk of developing venous thromboembolism (VTE) than those who seldom watch TV, and this is independent of physical activity, according to a meta-analysis.

Binge watching TV tied to increased risk of VTE

COVID-19 unlikely to be transmitted via breastfeeding, says small study

SARS-CoV-2 RNA is infrequently detected in the breastmilk of mothers with proven or suspected COVID-19, but just the same, breastfeeding does not represent a risk factor for vertical transmission of the infection, according to data from a small study.

COVID-19 unlikely to be transmitted via breastfeeding, says small study

26 Jan 2022

Mirikizumab improves disease, symptom severity in patients with Crohn’s disease

Treatment with the anti-interleukin-23p19 inhibitor mirikizumab led to significant improvements in patient-assessed disease severity and activity, as well as abdominal pain, in individuals with moderate-to-severe active Crohn’s disease, according to phase II data presented at the Crohn’s and Colitis Congress (CCC) 2022.

Mirikizumab improves disease, symptom severity in patients with Crohn’s disease

OCT allows noninvasive assessment of pulsatile intracranial pressure

Optical coherence tomography (OCT) can be used for the noninvasive measurement of pulsatile intracranial pressure, especially when using the OCT parameters peripapillary Bruch’s membrane angle and optic nerve head height, according to a recent study.

OCT allows noninvasive assessment of pulsatile intracranial pressure

SARS-CoV-2 antibodies persist long after infection

The majority of patients who contract SARS-CoV-2 infection develop antibodies, which remain in the blood for up to 15 months after infection, a study has found. Meanwhile, a negative antibody test is linked to re-infection.

SARS-CoV-2 antibodies persist long after infection

Glycated albumin predicts haemorrhagic transformation in IVT patients

Glycated albumin levels, as an estimator of prestroke glycaemic variability, is a good predictor of symptomatic haemorrhagic transformation in patients with intravenous thrombolysis (IVT), a recent study has found.

Glycated albumin predicts haemorrhagic transformation in IVT patients

Second-line tisagenlecleucel renders no EFS benefit in aggressive B-cell lymphoma

25 Jan 2022 bởi

The anti-CD19 chimeric antigen receptor (CAR) T-cell treatment tisagenlecleucel did not improve event-free survival (EFS) compared with standard care in patients refractory or who had progressed following first-line therapy for aggressive B-cell non-Hodgkin’s lymphoma, results of the phase III BELINDA trial showed.

Second-line tisagenlecleucel renders no EFS benefit in aggressive B-cell lymphoma

25 Jan 2022

Hyperuricaemia ups death risk in ICU patients with sepsis

In intensive care unit (ICU) patients with sepsis, hyperuricaemia correlates with significantly higher all-cause mortality and acute kidney injury, a recent study has found.

Hyperuricaemia ups death risk in ICU patients with sepsis

Investigative drug for ulcerative colitis passes muster in early trial

The orally administered, small molecule, gut-targeted stabiliser of hypoxia-inducible factor-1α (HIF-1α) GB004 appears to improve disease activity in patients with ulcerative colitis, with the drug being well-tolerated, according to the results of a phase Ib trial.

Investigative drug for ulcerative colitis passes muster in early trial

25 Jan 2022

Helicobacter pylori infection linked to greater carotid intima-media thickness

Individuals who are positive for Helicobacter pylori infection present with greater intima-media thickening of carotid artery, according to a study, suggesting that the infection may indirectly pose an increased risk of developing major vascular events.

Helicobacter pylori infection linked to greater carotid intima-media thickness