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The risk of suicide attempt is highest in the first 30 days following ideation diagnosis and is more common among women, combat medics, and soldiers with an anxiety disorder diagnosis prior to suicidal ideation and a same-day sleep disorder diagnosis, suggests a US study of army soldiers.

Suicide attempt more likely among women, combat medics, soldiers with anxiety disorder

Medical counselling boosts adherence to proper opioid disposal

Among families of postoperative paediatric patients, proper counselling by a medical professional improves adherence to proper opioid disposal guidelines, a recent study has found.

Medical counselling boosts adherence to proper opioid disposal

UC, CD duration does not affect treatment response to biologics

Disease duration of ulcerative colitis (UC) or Crohn’s disease (CD) does not seem to affect the proportional biologic-to-placebo treatment effect on remission, a new meta-analysis has found.

UC, CD duration does not affect treatment response to biologics

Symptomatic COVID-19 at pregnancy end tied to increased complications in mothers, infants

Expectant mothers with symptomatic COVID-19 upon hospital admission for delivery had a higher risk of emergency complications surrounding delivery, according to a small retrospective study from the US presented at Anesthesiology 2021. Furthermore, infants born to symptomatic mothers were more likely to require intensive care unit (ICU) admission or respiratory support.

Symptomatic COVID-19 at pregnancy end tied to increased complications in mothers, infants

12 Nov 2021

P53 status identifies BE patients at risk of progression

Abnormal p53 immunohistochemical (IHC) findings may indicate a higher risk of progression in Barrett’s oesophagus (BE) patients, a new study has found.

P53 status identifies BE patients at risk of progression

12 Nov 2021

Antiseizure drug yields durable seizure frequency reduction, lowers concomitant medication burden

In the treatment of adults with uncontrolled focal seizures, the long-term, open-label use of cenobamate appears to produce high rates of sustained 100-percent and ≥90-percent seizure reduction, with parallel decreases in concomitant antiseizure medication (ASM) doses, according to two separate post hoc analyses of a phase III C021 trial.

Antiseizure drug yields durable seizure frequency reduction, lowers concomitant medication burden

12 Nov 2021

Childhood abuse delays maturation specific to emotion circuits in girls

Girls who have been exposed to abuse have a delayed structural maturation pattern specific to emotion circuitry, which is potentially an adaptive mechanism that enhances threat generalization, a study has found. On the other hand, physical neglect correlates with a broader brain-wide pattern of advanced structural maturation.

Childhood abuse delays maturation specific to emotion circuits in girls

Metabolic dysfunction-associated fatty liver disease ups risk of severe COVID-19

Metabolic dysfunction-associated fatty liver disease (MAFLD) can escalate the incidence of severe COVID-19, but no association between MAFLD and COVID-19 death has been confirmed, suggest the results of a meta-analysis.

Metabolic dysfunction-associated fatty liver disease ups risk of severe COVID-19

12 Nov 2021

Larger wound size tied to severity, worse life quality in RDEB

In patients with recessive dystrophic epidermolysis bullosa (RDEB), larger wound size is predictive of worsening skin disease severity and quality of life (QOL), reports a recent study. Worsening skin disease severity is significantly associated with key clinical manifestations.

Larger wound size tied to severity, worse life quality in RDEB

Maintenance with ABC/3TC + RPV sustains virological suppression in HIV-1