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Sustained benefit with anti-TNFα less likely to lead to subsequent loss of response in IBD
Inflammatory bowel disease (IBD) patients receiving treatment with antitumour necrosis factor alpha (anti-TNFα) for more than 2 years represent a distinct group who obtain prolonged clinical benefit and tolerate maintenance treatment, according to a study.
Sustained benefit with anti-TNFα less likely to lead to subsequent loss of response in IBD
01 Nov 2021Poor metabolic health may lead to subsequent gastrointestinal cancers
Individuals with long-term metabolic syndrome are at increased risk of developing gastrointestinal cancer overall, including colorectal and pancreatic cancers and hepatocellular carcinoma, with the risk increase independent of genetic predisposition, a study has found.
Poor metabolic health may lead to subsequent gastrointestinal cancers
31 Oct 2021Local failure common in metastases from right-sided primary CRC treated with SABR
Local failure (LF) is more likely to occur in colorectal cancer (CRC) metastases treated with stereotactic ablative radiotherapy (SABR) if originating from right-sided primary CRC compared with left-sided, a study has found. In addition, LF rates are highest with liver metastases than other metastatic sites.
Local failure common in metastases from right-sided primary CRC treated with SABR
31 Oct 2021Novel SGLT2 inhibitor cuts HbA1c, plasma glucose, body weight in type 2 diabetes
Ertugliflozin, a novel sodium-glucose cotransporter inhibitor, helps reduce glycated haemoglobin (HbA1c), body weight, and fasting plasma glucose (FPG) in patients with type 2 diabetes, reports a recent meta-analysis.
Novel SGLT2 inhibitor cuts HbA1c, plasma glucose, body weight in type 2 diabetes
31 Oct 2021Air pollution compromises exercise responses more in healthy people than ex-smokers
Exposure to traffic-related air pollution takes a toll on exercise responses among healthy people but not former smokers with or without chronic obstructive pulmonary disorder (COPD), a study has found.
Air pollution compromises exercise responses more in healthy people than ex-smokers
31 Oct 2021Patients presenting with advanced-stage pancreatic cancer reveal cracks in imaging-based surveillance
High-risk individuals who develop neoplastic progression to pancreatic cancer or high-grade dysplasia can present at an advanced stage despite showing no lesions during prior imaging surveillance evaluations, a new study has found.