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Triple G agonist shows therapeutic potential in obesity
Treatment with retatrutide, the novel agonist of the glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and glucagon receptors, leads to marked reductions in body weight in individuals with obesity, as shown in the results of a phase II trial.
Triple G agonist shows therapeutic potential in obesity
11 Sep 2023HEART-FID confirms IV iron safety for HF but falls short in efficacy
The HEART-FID trial narrowly missed its primary endpoint, showing modest improvement in all-cause mortality, heart failure hospitalizations (hHF), and exercise function with ferric carboxymaltose (FCM) in HFrEF* patients with iron deficiency (ID).
HEART-FID confirms IV iron safety for HF but falls short in efficacy
11 Sep 2023Dapagliflozin safe, effective in HF patients across global regions
Dapagliflozin for individuals with heart failure (HF) demonstrates consistent safety and efficacy across regions worldwide despite geographic differences in patient characteristics, background treatment, and event rates, reports a recent study.
Dapagliflozin safe, effective in HF patients across global regions
08 Sep 2023Hydrocortisone cuts mortality risk in ICU patients with severe pneumonia
In patients admitted to the intensive care unit (ICU) for severe community-acquired pneumonia (CAP), those who received hydrocortisone had a lower mortality risk compared with those on placebo, findings from the CAPE COD* trial suggest.