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Ten years since the implementation of antimicrobial stewardship programmes (ASP) in Singapore, the use of several types of antibiotics has dropped, followed by reductions in antimicrobial resistance across several classes, as reported in a study.

Antibiotic use, resistance rates low after a decade of stewardship efforts in SG

AI predicts blood concentration of quetiapine in patients with schizophrenia, depression

A machine learning model that incorporates artificial intelligence (AI) techniques to predict the blood concentration of quetiapine is feasible for clinical medication guidance in patients with schizophrenia and depression, reports a real-world study.

AI predicts blood concentration of quetiapine in patients with schizophrenia, depression

31 Aug 2023

US FDA greenlights first pill for postpartum depression

The US Food and Drug Administration (FDA) has approved the first oral medication for postpartum depression in adults, giving clinicians a new therapeutic option for this debilitating condition.

US FDA greenlights first pill for postpartum depression

Statin cuts CV risk in patients with HIV

Treatment with pitavastatin is associated with a significantly lower risk of cardiovascular (CV) events in people living with human immunodeficiency virus (HIV) as shown in the final analysis of the double-blind, placebo-controlled REPRIEVE trial presented at IAS 2023.

Statin cuts CV risk in patients with HIV

Jakinibs for AD in Asians: Is one better than the other?

Treatment with oral Janus kinase (JAK) inhibitors or jakinibs appeared well tolerated in patients with atopic dermatitis (AD) as shown in an Asian retrospective cohort study.

Jakinibs for AD in Asians: Is one better than the other?

Nirmatrelvir–ritonavir combo averts hospitalization in high-risk COVID patients

Treatment with nirmatrelvir plus ritonavir appears to reduce the incidence of hospitalization in a highly vaccinated population of high-risk COVID-19 patients in Malaysia, as shown in a study.

Nirmatrelvir–ritonavir combo averts hospitalization in high-risk COVID patients

Does misoprostol reduce risk of NSAID-induced kidney injury?

Misoprostol, a prostaglandin E1 analogue used to prevent nonsteroidal anti-inflammatory drug (NSAID)-related gastrointestinal disorders, appears effective in preventing kidney injury associated with chronic NSAID use, but the quality of evidence is very low, results of a recent study have shown.

Does misoprostol reduce risk of NSAID-induced kidney injury?

Do weak opioids increase risk of GI cancers?

Evidence on the association of weak opioids with a higher risk of oesophageal and colorectal cancer is not reliable, but there appears to be a small association with gastric cancer, suggests a study.

Do weak opioids increase risk of GI cancers?

30 Aug 2023

Novel systemic therapies improve survival in prostate cancer patients with visceral metastasis

Novel systemic treatments are similarly effective in reducing the risk of progression or death in patients with metastatic hormone-sensitive (mHSPC) and castration-resistant prostate cancer (mCRPC), irrespective of visceral metastasis status, reports a study.

Novel systemic therapies improve survival in prostate cancer patients with visceral metastasis

30 Aug 2023

Phác đồ chu phẫu dựa trên duvalumab cải thiện kết cục ở bệnh nhân ung thư phổi không tế bào nhỏ (NSCLC) có thể phẫu thuật được.

Kết quả từ nghiên cứu AEGEAN cho thấy, ở những bệnh nhân ung thư phổi không tế bào nhỏ (NSCLC) có thể phẫu thuật được, thêm durvalumab chu phẫu vào hóa trị tân hỗ trợ cải thiện đáp ứng hoàn toàn về mặt mô bệnh học (pCR) và sống còn không biến cố (EFS).

Phác đồ chu phẫu dựa trên duvalumab cải thiện kết cục ở bệnh nhân ung thư phổi không tế bào nhỏ (NSCLC) có thể phẫu thuật được.