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SABR hits efficacy, safety targets for NSCLC with interstitial lung disease

In the treatment of patients with interstitial lung disease (ILD) and early-stage non–small cell lung cancer (NSCLC), stereotactic ablative radiotherapy (SABR) has met the prespecified acceptability thresholds for both toxicity and efficacy, according to the single-arm, phase II ASPIRE-ILD study.

SABR hits efficacy, safety targets for NSCLC with interstitial lung disease

Dupilumab sustains histological remission in children with EoE

29 May 2024 bởi

Treatment with higher-dose dupilumab results in sustained improvements in histologic and endoscopic measures of eosinophilic esophagitis (EoE) in children, regardless of prior use of swallowed topical corticosteroids (STCs), according to a subanalysis presented at ESPGHAN 2024.

Dupilumab sustains histological remission in children with EoE

Can mental disorders spread among teens within peer groups?

A Finnish teen study suggests that mental disorders may be transmitted socially via peer networks, such that having friends who have a diagnosis of mental disorders may put adolescents at risk of receiving one themselves.

Can mental disorders spread among teens within peer groups?

Metformin plus liraglutide eases glycemia but not gluconeogenesis in youth-onset T2D

Use of metformin with or without liraglutide results in improved glycaemia but falls short of suppressing the high rates of gluconeogenesis in patients with youth-onset type 2 diabetes (Y-T2D), reports a study.

Metformin plus liraglutide eases glycemia but not gluconeogenesis in youth-onset T2D

28 May 2024

Dupilumab lessens symptoms, betters life quality in atopic hand and foot dermatitis

Treatment with dupilumab substantially improves symptoms, quality of life, and other outcomes in patients with atopic hand and foot dermatitis (H/F AD), with an acceptable safety profile, results of a study have shown.

Dupilumab lessens symptoms, betters life quality in atopic hand and foot dermatitis

28 May 2024

Life quality drops then steadily improves after thyroidectomy in DTC patients

Patients with differentiated thyroid cancer (DTC) may experience a significant decline in health-related quality of life (HR-QoL) 3 months after thyroidectomy, but their HR-QoL will gradually improve and even exceed preoperative QoL by year 5, suggests a study.

Life quality drops then steadily improves after thyroidectomy in DTC patients

Earlier menopause, higher CV risk may lead to cognitive decline

Earlier menopause (occurring before age 49) coupled with higher risk of cardiovascular disease (CVD) is associated with an increased risk of cognitive problems later in life, a study suggests.

Earlier menopause, higher CV risk may lead to cognitive decline

28 May 2024

Dietary vitamins C and E may protect against aortic aneurysm, dissection

People with higher intakes of vitamins C and E in their diet appear to be at lower risk of aortic aneurysm and aortic dissection, as shown in a study.

Dietary vitamins C and E may protect against aortic aneurysm, dissection

Maralixibat may benefit certain subgroups of children with PFIC

Maralixibat may have a role in treating a broader profile of children with PFIC, including those who have had biliary diversion surgery and those with MDR3 deficiency, suggest subgroup analyses from the phase III MARCH/MARCH-ON trials

Maralixibat may benefit certain subgroups of children with PFIC