Tin tức & Cập nhật

Surveillance of favourable-risk patients with metastatic renal cell carcinoma (mRCC) using risk stratification based on the International mRCC Database Consortium (IMDC) and number of metastatic sites may be done following cytoreductive nephrectomy without initiating systemic therapy, suggests a recent study.

An integrated analysis of the pivotal phase IIb/III ALLEGRO and phase III ALLEGRO-LT studies demonstrated the long-term efficacy of the oral JAK3/TEC family kinase inhibitor ritlecitinib for alopecia areata (AA).

Risperidone use among patients with schizophrenia appears to confer some protection against the risk of kidney function decline, as reported in a study.

Maintenance therapy with niraparib appears to increase progression-free survival (PFS) in patients with advanced ovarian cancer, irrespective of postoperative residual disease or biomarker status, according to data from the phase III PRIME study.

Vardenafil (VDF), an effective treatment for erectile dysfunction, administered by an intranasal spray formulation achieves faster but similar plasma concentration with only about one-third dose relative to oral VDF tablet, according to a study.

In patients with lenalidomide-refractory multiple myeloma (MM), a single infusion of ciltacabtagene autoleucel (cilta-cel), a dual-binding BCMA*-directed chimeric antigen receptor (CAR) T-cell therapy, improved progression-free survival (PFS) compared with standard of care** (SoC), according to the phase III CARTITUDE-4 trial.