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Among patients with pharmacoresistant epilepsy who underwent surgery, those with an incomplete resection of a magnetic resonance imaging‐defined cortical lesion are at risk of late seizure recurrence, as shown in a study.

Complete resection key to sustained long‐term seizure freedom

ORZORA: Maintenance olaparib shows benefit in BRCA-mutated ovarian cancer

07 May 2021 bởi

Maintenance treatment with olaparib showed progression-free survival (PFS) benefit in patients with platinum-sensitive relapsed ovarian cancer (PSR OC), particularly those with somatic BRCA mutation (BRCAm), according to results of the ORZORA* trial presented at SGO 2021.

ORZORA: Maintenance olaparib shows benefit in BRCA-mutated ovarian cancer

Unhappy marriages increase men’s risk of stroke and all-cause mortality

07 May 2021 bởi

After more than three decades of follow-up, a prospective cohort study of nearly 9,000 men finds dissatisfaction with married life to be associated with increased long-term risk of stroke and all-cause mortality.

Unhappy marriages increase men’s risk of stroke and all-cause mortality

Low-dose ionizing radiation as a potential treatment for Alzheimer’s disease

07 May 2021 bởi

Results of a small single-arm study in Canada suggest that low-dose ionizing radiation (LDIR) may be a promising therapy for Alzheimer’s disease (AD).

Low-dose ionizing radiation as a potential treatment for Alzheimer’s disease

Lenvatinib + pembrolizumab improves survival in advanced endometrial cancer

In patients with advanced endometrial cancer with prior platinum chemotherapy exposure, a combination of lenvatinib + pembrolizumab improved survival compared with physician’s choice of treatment (TPC), results of the phase III Study 309/KEYNOTE-775 trial showed.

Lenvatinib + pembrolizumab improves survival in advanced endometrial cancer

Short sleep during midlife ups dementia risk in old age

Persistently short sleep during midlife appears to exacerbate the risk of dementia in old age, a recent study has found.

Short sleep during midlife ups dementia risk in old age

Reproxalap relieves itchy eyes in patients with allergic conjunctivitis

In patients with allergic conjunctivitis, treatment with the novel reactive aldehyde species (RASP) inhibitor reproxalap appears to produce a dramatic reduction in ocular itching, according to the results of the ALLEVIATE trial.

Reproxalap relieves itchy eyes in patients with allergic conjunctivitis

Automated performance metrics may predict outcomes during robotic partial nephrectomy

A recent study has shown that expert surgeons are more efficient and focused in their movement during robot-assisted partial nephrectomy. In addition, automated performance metrics during key steps are associated with objective measures of tumour complexity and may predict clinical outcomes.

Automated performance metrics may predict outcomes during robotic partial nephrectomy

LDL-C levels do not predict ischaemic stroke in AF patients on DOACs

No association exists between low-density lipoprotein cholesterol (LDL-C) levels and ischaemic stroke risk among patients with atrial fibrillation (AF) treated with direct oral anticoagulants (DOACs).

LDL-C levels do not predict ischaemic stroke in AF patients on DOACs

COVID-19 single-shot vax cleared for use again

Johnson & Johnson’s single-shot COVID-19 vaccine is safe for use in individuals 18 years of age and older, but it will likely come with a warning label, says the US Centers for Disease Control and Prevention (CDC).

COVID-19 single-shot vax cleared for use again