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Repotrectinib shows high response rates, durable activity in ROS1 fusion–positive NSCLC
The next-generation ROS1 and TRK tyrosine kinase inhibitor (TKI) repotrectinib has demonstrated high response rates and durable activity in patients with ROS1 fusion–positive non-small-cell lung cancer (NSCLC), regardless of whether they have previously received ROS1 TKI therapy, according to phase II results of the ongoing registrational TRIDENT-1 trial.
Repotrectinib shows high response rates, durable activity in ROS1 fusion–positive NSCLC
15 Jan 2024
Resection plus chemo improves survival in patients with UCR-MAC-LM
Primary tumour resection (PTR) in combination with chemotherapy (C) appears beneficial to a specific subgroup of patients with unresectable colorectal mucinous adenocarcinoma with liver metastasis (UCR-MAC-LM) compared with PTR or C alone, suggests a study.
Resection plus chemo improves survival in patients with UCR-MAC-LM
14 Jan 2024
Voice-based AI makes insulin management a breeze for T2D patients
A voice-based conversational artificial intelligence application helps type 2 diabetes (T2D) patients navigate basal insulin titration at home and, in turn, achieve rapid glycaemic control, as reported in a study.
Voice-based AI makes insulin management a breeze for T2D patients
13 Jan 2024
Maintenance olaparib rechallenge improves PFS in ovarian cancer patients
Restarting treatment with maintenance olaparib in ovarian cancer patients who had received one prior poly(ADP-ribose) polymerase (PARP) inhibitor and at least two lines of platinum-based chemotherapy results in a modest but significant improvement in progression-free survival (PFS) compared with placebo, results of a phase III study have shown.
Maintenance olaparib rechallenge improves PFS in ovarian cancer patients
13 Jan 2024
Survivors cope with life after testicular cancer
Testicular cancer survivors (TCSs) demonstrate similar health-related quality of life (HRQoL) to that of the general population at a median of 28 years since treatment initiation, reports a study.