Tin t&#x1EE9;c &amp; C&#x1EAD;p nh&#x1EAD;t

The presence and severity of nonalcoholic fatty liver disease (NAFLD) may contribute to cognitive impairment, as well as hippocampal structure and functional abnormalities, suggests a study.

NAFLD ups risk of memory impairment, hippocampal damage

Coming on the heels of the second interim analysis, the protocol-specified final invasive disease-free survival (iDFS) analysis of the phase III NATALEE trial continues to show a highly significant iDFS benefit with the combination of the CDK 4/6 inhibitor ribociclib and a nonsteroidal aromatase inhibitor (NSAI) in individuals with HR+/HER2- early breast cancer.

Add-on ribociclib continues to triumph in early breast cancer

20 Dec 2023 bởi

Add-on ribociclib continues to triumph in early breast cancer

20 Dec 2023

Cilostazol safe but not neuroprotective

In the treatment of people with mild cognitive impairment, cilostazol is well tolerated but falls short of preventing further cognitive decline, according to the results of the phase II COMCID* trial.

Cilostazol safe but not neuroprotective

Daily smoking linked to smaller brains

Smoking daily may cause the brain to shrink in a dose-response manner, and quitting does not seem to reverse the brain volume loss, as reported in a study.

Daily smoking linked to smaller brains

Most HF patients do not undergo loop diuretic dose reduction after SGLT2i initiation

Majority of the patients with heart failure (HF) who have initiated treatment with sodium-glucose cotransporter 2 inhibitor (SGLT2i) show no change in loop diuretic dose, reports a study.

Most HF patients do not undergo loop diuretic dose reduction after SGLT2i initiation

19 Dec 2023

Smartphone-based intervention helps improve mental health of university students

Mobile Mindfulness Meditation (MMM) demonstrates effectiveness in reducing stress and anxiety among university students, leading to better mental health, according to a study.

Smartphone-based intervention helps improve mental health of university students

19 Dec 2023

Antipsychotic use for amphetamine-induced psychosis tied to longer hospital stay

Patients with amphetamine-induced psychosis (AIP) who have been treated with antipsychotics appear to have a longer length of stay (LOS) than those who did not receive such treatment, reports a study.

Antipsychotic use for amphetamine-induced psychosis tied to longer hospital stay

Real-world data highlight tofacitinib potential for irAE management in cancer patients

In a study presented at ESMO Asia 2023, tofacitinib, a rapidly acting JAK-STAT inhibitor with reported efficacy in the treatment of various autoimmune diseases, was effective for the management of difficult-to-treat immune-related adverse events (irAEs) and was well-tolerated in cancer patients, with only a few patients developing infectious events.

Real-world data highlight tofacitinib potential for irAE management in cancer patients

Pregnancy after breast cancer safe for BRCA carriers

One in five young BRCA carriers with breast cancer subsequently conceive within 10 years, without any detrimental effect on disease-free survival, according to a study.

Pregnancy after breast cancer safe for BRCA carriers

19 Dec 2023

Add-on PCSK9 inhibitor cuts LDL-C by half, allows infrequent dosing in patients maxed out on statins

Injection with the novel, long-acting PCSK9 inhibitor recaticimab once every 3 months reduces LDL-cholesterol (LDL-C) levels by >50 percent compared with placebo in patients already maxed out on statins in the phase III REMAIN-2 trial.

Add-on PCSK9 inhibitor cuts LDL-C by half, allows infrequent dosing in patients maxed out on statins