Geriatric assessments refine cancer treatment in elderly, lead to better outcomes

18 Jun 2021
Geriatric assessments refine cancer treatment in elderly, lead to better outcomes

Geriatric assessment (GA) may help lower complication rate and length of stay among older patients with cancer without affecting 1-year mortality, a recent study has found.

Researchers retrospectively assessed 184 elderly patients with solid malignancies who had been referred to a surgical outpatient clinic. All participants underwent a nurse-led GA, the findings from which were incorporated in the discussions of an onco-geriatric multidisciplinary team (MDT) and could lead to modifications in management.

The study outcomes were 1-year all-cause mortality, postoperative complications and hospital length of stay, compared between groups that have had their management plans modified or unchanged.

Overall, 25 percent (n=46) saw modifications in their cancer management plans, while the approach was unchanged in 75 percent (n=138). One-year all-cause mortality was 28.8 percent for the overall sample and did not differ between the former and latter subgroups of patients (26.1 percent vs 29.7 percent, respectively; p=0.7).

Meanwhile, adjustments made by the MDT had a significant impact on postoperative complication rate, which was significantly lower in those whose management plans had been modified (13.0 percent vs 34.8 percent; p=0.005). In this overall analysis, needing no surgery was counted as having no complications. In the subgroup of patients who had undergone surgery, treatment modification had no impact on complication rate (p=0.2).

In addition, the researchers found that patients who had had their management plans adjusted stayed for a significantly shorter time than those whose care was unchanged (median, 5 vs 8.5 days; p=0.0020).

“[I]ncorporating geriatric assessment in treatment decision-making improved patient outcomes, without increasing one-year mortality rate. These data support broader implementation of geriatric assessment in oncology care,” the researchers said.

J Geriatr Oncol 2021;12:779-785