TVB-2640 impresses in nonalcoholic steatohepatitis
Use of the fatty acid synthase (FASN) inhibitor TVB-2640 in the treatment of patients with nonalcoholic steatohepatitis (NASH) yields dose-dependent improvements in liver fat as well as biochemical, inflammatory, and fibrotic biomarkers, according to the results of the phase IIa trial 3V2640-CLIN-005 (FASCINATE-1).