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Fibrosis-4 index predicts cardiovascular events in NAFLD
The fibrosis-4 index (FIB-4) is strongly and independently associated with major adverse cardiovascular events (MACE), beyond established cardiovascular risk factors and baseline liver diagnosis, among patients with nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), or at risk of NASH, a study in the real-world setting has shown.
Polypharmacy in IBD interferes with treatment adherence, therapeutic success
Polypharmacy (PP) arises in nearly one in five patients with inflammatory bowel disease (IBD), particularly in older adults and those with comorbidity, according to a study, adding that PP can complicate adherence to treatment and therapeutic success.
Record-high rise in alcohol-related hepatitis during pandemic a cause for alarm
Cases of severe alcohol-related hepatitis requiring inpatient management has dramatically increased during the COVID-19 pandemic, particularly in patients aged <40 years and in women, a study has found.
Whole-exome sequencing enhances diagnosis in young CRC patients
Whole-exome sequencing (WES) can improve diagnosis rates in young colorectal cancer (CRC) patients who show no pathogenic variants in mismatch repair (MMR) genes or in the adenomatous polyposis coli (APC) gene, reports a recent study.