Suicide risk factors among the Chinese

27 Mar 2021
Suicide risk factors among the Chinese

Among the Chinese, suicide appears to be more likely among men, the elderly, and people who are single, a recent study has found. Similarly, those with major physical illnesses or lifetime mental disorders are also more likely to die by suicide.

Researchers conducted a prospective analysis of 512,715 individuals (mean age 52 years, 41 percent men) enrolled from the China Kadoorie Biobank. Semi-structured interviews and self-report questionnaires were used to collect information about potential risk factors.

Over an average follow-up of 9.9 years, a total of 520 suicides were reported, yielding a rate of 101 cases per 100,000 people, or 10.2 per 100,000 annually. Just over half of the suicides (51.3 percent) were in men, though a large majority (79.8 percent) were in people who lived in rural areas.

Cox regression analysis found that men were 60-percent more likely to die by suicide than women (adjusted hazard ratio [aHR], 1.6, 95 percent confidence interval [CI], 1.4–2.0; p<0.001), as were those who were older (aHR per each 10-year increase, 1.3, 95 percent CI, 1.2–1.5; p<0.001).

Those who lived rurally (aHR, 2.6, 95 percent CI, 2.1–3.3; p<0.001) and were single (aHR, 1.7, 95 percent CI, 1.4–2.2) were also significantly more likely to die by suicide.

In addition, participants who had undergone family-related stressful life events (aHR, 1.8, 95 percent CI, 1.2–1.9; p<0.001) and were suffering from major physical illnesses (aHR, 1.5, 95 percent CI, 1.3–1.9; p<0.001) or lifetime mental disorders (aHR, 9.6, 95 percent CI, 5.9–15.6; p<0.001) saw similarly heightened risks. Psychiatric conditions such as schizophrenia-spectrum, depressive, anxiety, and sleep disorders were likewise linked to greater suicide risk.

PLoS Med 2021;doi:10.1371/journal.pmed.1003545