Primary Angle-Closure Glaucoma Disease Summary

Primary angle-closure is the synechial or appositional closure of the anterior chamber angle secondary to multiple mechanisms resulting in raised intraocular pressure (IOP) and structural changes in the eyes.
Iridotrabecular contact is the hallmark of primary angle-closure  and the most commonly identified sign  wherein the iris appears to touch the anterior chamber angle at the posterior pigmented trabecular meshwork or more anterior structures, and indicates that treatment is required which indicates that treatment is required.
Primary angle-closure glaucoma is the presence of glaucomatous optic neuropathy.
Medical therapy is the initial treatment of acute angle-closure that is directed towards lowering the IOP to relieve acute symptoms and potential harm of high IOP.
Laser peripheral iridotomy is the definitive treatment of acute and chronic angle-closure glaucoma with a pupillary block component. It is the preferred surgical treatment due to its favorable risk-benefit ratio.

For further information regarding the management of Primary Angle-Closure Glaucoma, please refer to Disease Algorithm for the Treatment Guideline.