Dragon fruit improves vascular function in adults

18 May 2022
Dragon fruit improves vascular function in adults

Eating dragon fruits leads to better endothelial function and improvements in arterial stiffness in healthy individuals, a study has shown.

“This implies that regular dragon fruit consumption may have a meaningful impact on cardiovascular disease risk likely due to [its] high betalain content,” the authors said.

In this randomized, double-blind, placebo-controlled, crossover trial, the authors examined the effects of acute and short-term consumption of dragon fruit on vascular function in a healthy population. Nineteen young, healthy, nonsmoking men and women were randomly assigned to consume 24-g whole dragon fruit powder (33-mg betalains) or a nutrient-matched placebo daily for 14 days.

The authors measured flow-mediated dilation (FMD), arterial stiffness, and blood pressure (BP) at 0, 1, 2, 3, and 4 hours and finally at 14 days after daily consumption.

Eighteen of the 19 participants completed the trial. Dragon fruit consumption led to significantly better acute FMD at 2 hours (0.8 percent; p=0.01), 3 hours (1.0 percent; p=0.001), and 4 hours (1.3 percent; p<0.001) postconsumption relative to placebo. Such effect persisted until day 14 (1.3 percent; p<0.001).

Eating dragon fruits also significantly reduced pulse-wave velocity at 3 hours (‒0.5 m/s; p=0.003) and improved augmentation index after 14 days (‒7.0 percent; p=0.02) compared with placebo. Of note, there were no differences seen in either peripheral or central blood pressure across time points.

“Betalains are natural red colour pigments abundant in red-fleshed dragon fruit,” the authors said. “Recent research has shown that dragon fruit consumption may help improve blood glucose and lipid profile.”

Am J Clin Nutr 2022;115:1418-1431