At the recent MPN Expert Forum held in Kuching, Dr Chew Lee Ping (Consultant Haematologist, Sarawak General Hospital) and Dr Yong Kar Ying (Clinical Haematologist Hospital Miri Sarawak) shared their expert opinion on treating hydroxyurea (HU) resistance/intolerance in Polycythaemia Vera (PV) patients, where real-life patients were managed successfully.