Ranolazine: A Safe and well – Tolerated Anti-Ischaemic Agent

Coronary artery disease (CAD) stands as the foremost cause of mortality worldwide. In 2012, CAD accounted for 98.9 deaths per 100,000 people in Malaysia. Chronic stable angina is a common manifestation of CAD.  The presence of chronic angina significantly increases the risk of major cardiovascular (CV) events, reduces quality of life (QoL) and adversely affects activities of daily living. Patients with this condition often present with several comorbidities, including hypertension, diabetes mellitus (DM),dyslipidaemia, atrial fibrillation (AF) and heart failure, further complicating the treatment approach.